Zyloprim 300mg Tablets 60


Drug Name: allopurinol
Our Price $9.50
PBS $14.09
Concession $8.45
Safety Net $2.85

S8 Note - This prescription item is Schedule 8 and can only be supplied on a script from a registered doctor in Queensland. Any prescriptions from any other state cannot be filled and will be returned in the mail

Note: Private, PBS and our prices are available to the general public. Concession and Safety Net prices are only available to people with the appropriate concession or Safety Net cards. See Prescriptions for more details.


This prescription item requires a pre approved authority from the Government in order to get this item at the quoted price. Authority prescriptions need to be applied for by the doctor writing the script and can include reasons such as increased quantities due to dosage, increased repeats, use for a pre determined specified use, or the nature of the medication itself requiring specialist interaction. In the event that an authority is not granted on the script, the price will revert to the private price quoted for that item


This item contains more than one pack of a prescription product. Before this can be dispensed the doctor has to give approval. The prescription must be written for the total quantity or the prescription must be endorsed by your doctor "Regulation 24" otherwise we will be unable to dispense the increased amount. If you proceed with the order without approval, we will only send out one pack at the single pack price and refund the difference. Eg If your prescription is written out for 30 Tablets with 5 repeats and it does not have “Regulation 24 “ written on the script, the ONLY quantity we can dispense is 30 at one time. Further dispensing of this product could only occur after an appropriate length of time - usually 21 days but depends on dosage. In this example if you would like to obtain 180 Tablets then the doctor must endorse the prescription “Regulation 24” or the quantity must be written out for 180 and not 30. NB Conditions apply on the writing of a Regulation 24 prescription. Ask your doctor or pharmacist for details.

We can no longer accept signed authority forms from your doctor as permission to dispense more than one pack. Please contact our pharmacist for more information.

If you order this item as Private, NO PBS stickers will be issued. Once any prescription order has been sent the product cannot be returned for a refund even if your doctor changes your medication or you have an adverse reaction.

Zyloprim 300mg Tablets 60

Zyloprim 300mg Tablets 60

Product ID: 8512

Pharmacist Only Medicine

This product is a Pharmacist Only Medicine and requires pharmacist advice before we can dispatch this product. You must first place the order and then contact our pharmacists within 48 hours on 1300 367 283. The pharmacist will determine if this product is appropriate for you and if so, approve the order. In the event that you do not do this, the product will be deleted from your order and the balance of your order will be dispatched. This is not required if you have a doctor's prescription.


General Information

Consumer Medicine Information

What is in this leaflet

This leaflet answers some common questions about ZYLOPRIM (Allopurinol tablets).It does not contain all of the available information about ZYLOPRIM tablets.It does not replace talking to your doctor or pharmacist.All medicines have risks and benefits. Your doctor has weighed the risks of you or your child taking ZYLOPRIM against the benefits he or she expects it will have.If you have any concerns about taking this medicine, ask your doctor or pharmacist.

Keep this leaflet with the medicine. You may need to read it again.


The name of your medicine is ZYLOPRIM and is available in tablets of two different strengths.The active ingredient is calledallopurinol.Allopurinol belongs to a group of medicines called anti-uricaemic agents and is used to reduce the amount of uric acid in the body. Most commonly, high levels of uric acid in the body are related to gout.ZYLOPRIM is available as a 100 mg and 300 mg tablet.What ZYLOPRIM is used forZYLOPRIM is used to treat high levels of uric acid in the blood (hyperuricaemia) associated with gout or some other conditions. Your doctor will identify these other conditions if necessary, as they are very uncommon (e.g. Lesch-Nyhan Syndrome).Your doctor however, may have prescribed ZYLOPRIM for another purpose not listed above.Ask your doctor if you have any questions about why ZYLOPRIM has been prescribed for you.

If you have any concerns, you should discuss this with your doctor.

This medicine is only available with a doctor's prescription.

Before you take ZYLOPRIM

When you must not take it

Do not take ZYLOPRIM if you are allergic to:
Allopurinol or any of the ingredients listed at the end of this leaflet including lactose.

Some of the symptoms of an allergic reaction to ZYLOPRIM may include urticaria and other skin rashes, difficulty breathing, hay fever, swelling of the face or throat or faintness.Do not take ZYLOPRIM after the expiry date (EXP.) printed on the pack. If you take it after the expiry date has passed, it may have no effect at all, or worse, there may be an entirely unexpected effect.

Do not purchase or take ZYLOPRIM if the packaging is torn or shows signs of tampering.

Do not take ZYLOPRIM if the tablets do not look quite right.

If you are not sure whether you should start taking ZYLOPRIM, contact your doctor or pharmacist.

Do not give ZYLOPRIM to children unless your doctor has prescribed it.

Before you start to take it

You must tell your doctor if you are:
1. Allergic to any other medicines or any other foods, dyes or preservatives

Some of the symptoms of an allergic reaction to ZYLOPRIM may include shortness of breath, wheezing or difficulty breathing; swelling of the face, lips, tongue or other parts of the body; rash, itching or hives on the skin.
2. You have or have had any medical/ health problems, including:
kidney disease
liver disease
high blood pressure
heart disease
haemochromatosis (a disease involving excessive deposits of iron in the body).
3. You are pregnant or plan to become pregnant

ZYLOPRIM like all medicines should not be used during pregnancy, unless your doctor tells you to.
4. You are breast-feeding or plan to breastfeed
5. Having an attack of gout

If a person first starts taking ZYLOPRIM when they are having an attack of gout it can make the symptoms of this condition temporarily worse. However, if an acute attack of gout does occur when a person is already taking ZYLOPRIM it can be continued. Do not stop taking ZYLOPRIM during an attack of gout unless advised by your doctor.If you have not told your doctor about any of the above, tell him or her before you start to take ZYLOPRIM.

Taking other medicines

Tell your doctor if you are taking any other medicines, including medicines that you buy without a prescription from a pharmacy, supermarket or health food shop.

SOME medicines may interfere with ZYLOPRIM.

These include:
Aspirin (a drug which is used to treat headache, pain, inflammation, clotting or high temperatures). Other salicylate type drugs are also included. Ask your pharmacist.
Coumarin type anticoagulant drugs, medicine used to prevent blood clots (e.g. warfarin)
Other medicines used to treat gout or hyperuricaemia such as probenecid (Benemid)
Some medicines used to suppress the immune system such as azothioprine (Imuran), 6- mercaptopurine and cyclosporin
Some medicines used to treat epilepsy such as phenytoin (Dilantin)
Theophylline (a drug used to treat asthma)
Ampicillin or amoxycillin, which are two commonly used antibiotics used to treat bacterial infections
Chlorpropamide (Diabinese) used to treat diabetes
Medicines containing thiazide diuretics, used to decrease blood pressure and fluid retention (e.g. Chlorothiazide, hydrochlorothiaide, bendrofluazide)

The above medicines may either reduce the effectiveness of ZYLOPRIM, reduce its own effectiveness and/or react with ZYLOPRIM resulting in untoward or sometimes dangerous side effects.This list is not exhaustive. Your doctor or pharmacist has more information on medicines to be careful with or avoid while taking ZYLOPRIM.How to take ZYLOPRIMHow much to take

The dose of ZYLOPRIM may be different for each person and their medical condition. Your doctor will decide the right dose for you.The recommended doses are for:
Adults: Usually 100 mg to 600 mg daily in divided doses (that is one 100 mg tablet daily up to one 300 mg tablet twice daily), but the dose may be as much a 900 mg daily to treat very high blood levels of uric acid.
Children under 15 years: 100 mg to 400 mg daily in divided doses.
Elderly patients usually receive the lowest dose possible to control uric acid production.

How to take ZYLOPRIM

Swallow the tablets with plenty of water and after food to reduce the possibility of gastric upset.When to take it

Take ZYLOPRIM immediately after meals at the frequency directed by your doctor. For example, morning and night after breakfast and dinner for a twice daily dosage.If you forget to take it

If your dosing schedule is one dose a day, take the missed dose as soon as possible, but not later than 4 hours before your next dose.

If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to.

Otherwise, take it as soon as you remember, and then go back to taking it as you would normally.

Do not take a double dose to make up for the dose that you missed.

If you are unsure about whether to take your next dose, speak to your doctor or pharmacist.

Do not try to make up for missed doses by taking more than one dose at a time. This may increase the chance of you getting an unwanted side effect.

If you have trouble remembering when to take your medicine, ask your pharmacist for some hints.

If you take too much (Overdose)

Immediately telephone your doctor or Poisons Information Centre (telephone 13 11 26) for advice, or go to Accident and Emergency at your nearest hospital, if you think that you or anyone else may have taken too much ZYLOPRIM. Do this even if there are no signs of discomfort or poisoning. Also, report any other medicines or alcohol which has been taken. You may need urgent medical attention.

Keep telephone numbers for these places handy.

If you take too much ZYLOPRIM you may have the following symptoms: nausea, vomiting and diarrhoea.

While you are taking ZYLOPRIM

Things you must do

Immediately stop taking ZYLOPRIM and check with your doctor if a skin rash or other allergic reaction occurs.Take ZYLOPRIM exactly as your doctor has prescribed.It is important to drink at least 2 litres of fluid per day. This will help prevent kidney stones.ZYLOPRIM helps prevent, but does not relieve gout attacks. It is important that you continue taking ZYLOPRIM with the medication prescribed for gout attacks.Tell all doctors, dentists and pharmacists who are treating you that you are taking ZYLOPRIM.Tell your doctor (immediately) if you become pregnant while you are taking ZYLOPRIM.Visit your doctor regularly. Your doctor needs to check your progress and see whether you need to keep taking ZYLOPRIM.Always discuss with your doctor any problems or difficulties during or after taking ZYLOPRIM.Tell your doctor if for any reason, you have not taken your medicine exactly as prescribed. Otherwise your doctor may think that it was not effective and change your treatment unnecessarily.Keep enough ZYLOPRIM to last weekends and holidays.Things you must not do

Do not take any other medicine while you are taking ZYLOPRIM without first telling your doctor.Do not drive, operate machinery, or participate in any dangerous activities where alertness is required, until you know how ZYLOPRIM affects you.

ZYLOPRIM may cause dizziness and affect co-ordination in some people. Therefore, it may affect alertness or concentration. ZYLOPRIM can also affect your eyesight.

Make sure you know how you react to ZYLOPRIM before you drive a car, operate machinery or do anything else that could be dangerous if you are dizzy or have affected vision.

Do not take ZYLOPRIM for a longer time than your doctor has prescribed.

Do not change your dose without first checking with your doctor.

Do not stop taking ZYLOPRIM or lower the dose without checking first with your doctor.

Stopping this medicine suddenly on your own accord may cause some unwanted and dangerous effects, or your condition may reappear.

Your doctor will advise you when you can stop taking ZYLOPRIM completely.

Do not take this medicine to treat any other complaints unless your doctor tells you to.

Do not give this medicine to anyone else, even if their symptoms seem similar to yours.

Side effects

Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking ZYLOPRIM.

ZYLOPRIM helps most people with the medical conditions listed in the beginning of this leaflet, but it may have unwanted side effects in some people.

All medicines have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.

Ask your doctor or pharmacist any questions you may have.

Common side effects:

The most common side effect is skin rash. Stop treatment with ZYLOPRIM immediately and contact your doctor if a rash does occur.

Tell your doctor if you notice any of the following:
nausea (feeling sick)
oedema (swelling)
high blood pressure
abdominal pain
skin rash
blurred vision
unexplained nosebleeds

There are other side effects that occur less often.

If any of the following happen, stop taking ZYLOPRIM and tell your doctor immediately or go to Accident and Emergency at your nearest hospital:
fatty stools
going to the toilet often
blood in the urine
hair loss
general malaise or depression
confusion or vision problems
numbness in the limbs
angina (chest pain involving the heart)
severe palpitations
rash, itching or hives on the skin
swelling of the face, lips, tongue or other parts of the body
wheezing, shortness of breath, or trouble breathing
pain or tightness in the chest
if chills, fever, joint pain or swollen glands occur, especially if they occur together with or shortly after a skin rash

These are serious side effects.You may need urgent medical attention.Serious side effects are rare.Some people may get other side effects when taking ZYLOPRIM.Your doctor may lower the dose to help control any serious side effects and decide on the necessary tests to monitor any of the above problems.

Check with your doctor as soon as possible if you have any problems while taking ZYLOPRIM, even if you do not think the problems are connected with the medicine or are not listed in this leaflet.

After taking ZYLOPRIM


Keep it where children cannot reach it. A locked cupboard at least one and a half metres above the floor is a good place to store medicines.

Keep ZYLOPRIM in a cool dry place where the temperature stays below 30 deg C and protect from light. Do not store it or any other medicines in a bathroom or near a sink.

Do not leave it in the car or on windowsills. Heat and dampness can destroy some medicines.

Keep your tablets in the packs or bottles they were provided in until it is time to take them.


If your doctor tells you to stop taking this medication OR it has passed the expiry date, ask your pharmacist what to do with any left over.

Product Description

What it looks like

ZYLOPRIM 100 mg tablets are white to off-white, biconvex, round tablets coded with "U4A" and scored on the upper face, bottom face plain; in bottles of 200.ZYLOPRIM 300 mg tablets are white, biconvex, round tablets coded with "C9B" and scored on the upper face, bottom face plain; in blister packs of 60.Ingredients

Each ZYLOPRIM 100 mg and 300 mg tablet contains the active ingredient allopurinol.The non-active ingredients in each ZYLOPRIM tablet are:
maize starch
magnesium stearate

ZYLOPRIM tablets contain lactose but do not contain gluten or sucrose.

Sponsor or Supplier

Sigma Pharmaceuticals (Australia) Pty Ltd
(A.C.N. 004 118 594)
96 Merrindale Drive
CROYDON, Victoria, 3136

Telephone 03-9839 2800

The Australian Registration Numbers for ZYLOPRIM 100 mg and 300 mg tablets are AUST R 11016 and AUST R 11017 respectively.

This leaflet was prepared in March 2000 and updated in June 2001, January 2002, June 2003 and January 2006.

Preferred Generic
Our preferred generic for this medication is listed below. A generic prescription medicine works in the same way as the existing medicine. What matters is the active ingredient, which is the same in the generic brands and the existing brand. Please click on it below to view the product(s).
Allopurinol Sandoz 300mg Tablets 60
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Alternative Product(s)
There is generic brand to choose from in the table below. Generic Brands are less expensive brands that have been proven to have the same effect. Please select the desired brand.* *Some Doctor's will have "no substitution permitted" endorsed on the script. Please check your prescription as generics are not available in this case.
Allopurinol Sandoz 300mg Tablets 60
Progout 300mg Tablets 60
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