Renitec 20mg Tablets 30


Drug Name: enalapril
Our Price $13.99
PBS $20.62
Concession $9.85
Safety Net $4.65

S8 Note - This prescription item is Schedule 8 and can only be supplied on a script from a registered doctor in Queensland. Any prescriptions from any other state cannot be filled and will be returned in the mail

Note: Private, PBS and our prices are available to the general public. Concession and Safety Net prices are only available to people with the appropriate concession or Safety Net cards. See Prescriptions for more details.


This prescription item requires a pre approved authority from the Government in order to get this item at the quoted price. Authority prescriptions need to be applied for by the doctor writing the script and can include reasons such as increased quantities due to dosage, increased repeats, use for a pre determined specified use, or the nature of the medication itself requiring specialist interaction. In the event that an authority is not granted on the script, the price will revert to the private price quoted for that item


This item contains more than one pack of a prescription product. Before this can be dispensed the doctor has to give approval. The prescription must be written for the total quantity or the prescription must be endorsed by your doctor "Regulation 24" otherwise we will be unable to dispense the increased amount. If you proceed with the order without approval, we will only send out one pack at the single pack price and refund the difference. Eg If your prescription is written out for 30 Tablets with 5 repeats and it does not have “Regulation 24 “ written on the script, the ONLY quantity we can dispense is 30 at one time. Further dispensing of this product could only occur after an appropriate length of time - usually 21 days but depends on dosage. In this example if you would like to obtain 180 Tablets then the doctor must endorse the prescription “Regulation 24” or the quantity must be written out for 180 and not 30. NB Conditions apply on the writing of a Regulation 24 prescription. Ask your doctor or pharmacist for details.

We can no longer accept signed authority forms from your doctor as permission to dispense more than one pack. Please contact our pharmacist for more information.

If you order this item as Private, NO PBS stickers will be issued. Once any prescription order has been sent the product cannot be returned for a refund even if your doctor changes your medication or you have an adverse reaction.

Renitec 20mg Tablets 30

Renitec 20mg Tablets 30

Product ID: 7401

Pharmacist Only Medicine

This product is a Pharmacist Only Medicine and requires pharmacist advice before we can dispatch this product. You must first place the order and then contact our pharmacists within 48 hours on 1300 367 283. The pharmacist will determine if this product is appropriate for you and if so, approve the order. In the event that you do not do this, the product will be deleted from your order and the balance of your order will be dispatched. This is not required if you have a doctor's prescription.


General Information

Consumer Medicine Information

What is in this leaflet

This leaflet answers some common questions about VYTORIN. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist.

All medicines have risks and benefits. Your doctor has weighed the risks of you taking VYTORIN against the benefits they expect it will have for you.

If you have any concerns about taking this medicine, ask your doctor or pharmacist.

Keep this leaflet with the medicine. You may need to read it again.

What VYTORIN is used for

VYTORIN helps to lower cholesterol and triglyceride levels. It is used in people whose cholesterol levels are too high and when diet alone cannot lower these levels adequately.


Cholesterol is one of several fatty substances found in the bloodstream. Your total cholesterol is made up mainly of LDL and HDL cholesterol.

LDL cholesterol is often called 'bad' cholesterol because it can build up in the walls of your arteries forming plaque. Eventually this plaque build-up can lead to a narrowing of the arteries.

This narrowing can slow or block blood flow to vital organs such as the heart and brain. This blocking of blood flow can result in a heart attack or stroke.

HDL cholesterol is often called 'good' cholesterol because it helps keep the bad cholesterol from building up in the arteries and protects against heart disease.


Triglycerides are another form of fat in your blood that may increase your risk for heart disease.

How VYTORIN works

VYTORIN reduces elevated total-cholesterol, LDL (bad) cholesterol and triglycerides and increases HDL (good) cholesterol.

VYTORIN works by decreasing the absorption of cholesterol in the small intestine and by reducing the amount of cholesterol made in the liver. VYTORIN does not help you lose weight.

Your doctor may have prescribed VYTORIN for another reason. Ask your doctor if you have any questions about why VYTORIN has been prescribed for you.

VYTORIN is not addictive.

VYTORIN is not recommended for use in children, as there have been no studies of its effects in children.

Before you take VYTORIN

When you must not take it

Do not take VYTORIN if:
you have an allergy to VYTORIN or any of the ingredients listed at the end of this leaflet.
Symptoms of an allergic reaction may include skin rash, itchiness, shortness of breath, swelling of the face, lips, mouth, tongue or throat.
you are pregnant or breast feeding.
Your baby may absorb this medicine in the womb or from breast milk and therefore there is a possibility of harm to the baby.
you have active liver disease or repeated blood tests indicating possible liver problems.
you have had muscle pain, tenderness or weakness from other medicines used to treat high cholesterol or triglycerides.
the packaging is torn or shows signs of tampering.
the expiry date on the pack has passed.
If you take this medicine after the expiry date has passed, it may not work.

If you are not sure whether you should start taking VYTORIN, talk to your doctor.

Before you start to take it

Tell your doctor if:
1. you are pregnant or intend to become pregnant.
VYTORIN should not be used during pregnancy.
2. you are breast-feeding.
VYTORIN should not be used while breast feeding.
3. you have unexplained muscle pain, tenderness or weakness not caused by exercise.
Your doctor may do a blood test to check for certain muscle problems.
4. you have, or have had, any medical conditions, including liver disease or liver problems.
Your doctor will do a blood test to make sure you have no problems with your liver.
5. you have kidney disease or any other medical problems.
6. you drink alcohol regularly.
7. you have any allergies to any other medicines or any other substances, such as foods, preservatives or dyes.

If you have not told your doctor about any of the above, tell them before you take any VYTORIN.

Taking other medicines

Tell your doctor if you are taking any other medicines, including medicines that you buy without a prescription from your pharmacy, supermarket or health food shop. Some medicines should not be taken with VYTORIN. These include:
nefazodone, used to treat depression
protease inhibitors, used to treat HIV infection, including indinavir, nelfinavir, ritonavir, saquinavir
erythromycin, clarithromycin and fusidic acid, antibiotics used to treat infections
ketoconazole and itraconazole, used to treat certain fungal infections

If you are taking any of the above, your doctor may suggest stopping VYTORIN temporarily or permanently.

Some medicines and VYTORIN may interfere with each other. These include:
bile acid sequestrants, such as cholestyramine, used to lower cholesterol levels.
other medicines to lower cholesterol levels, for example gemfibrozil, other fibrates, nicotinic acid (also known as niacin).
warfarin, used to prevent blood clots
cyclosporin, used to suppress the immune system
verapamil, used to treat high blood pressure and angina
diltiazem, used to treat angina
amiodarone, used to treat irregular heart beat
digoxin, used to treat heart failure

These medicines may be affected by VYTORIN, may affect how well it works, or may increase the risk of side effects with VYTORIN. You may need different amounts of your medicine, or you may need to take different medicines or take your medicines at different times.

Your doctor or pharmacist has more information on medicines to be careful with or avoid while taking VYTORIN.

How to take VYTORIN

How much to take

Take VYTORIN only when prescribed by your doctor.

The recommended dose is one VYTORIN 10/10, 10/20, 10/40 or 10/80 tablet once a day, in the evening.

Swallow VYTORIN with a glass of water.

Follow all directions given to you by your doctor and pharmacist carefully. They may differ from the information contained in this leaflet.

If you do not understand the instructions, ask your doctor or pharmacist for help.

When to take it

VYTORIN should be taken once a day, in the evening.

The liver produces its greatest amount of cholesterol when the body is at rest and when there is no dietary intake. For most people this is at night when asleep. Therefore, VYTORIN is more effective when taken in the evening. A good time would be after your evening meal. However, it does not matter whether you take it before or after food.

However, take VYTORIN about the same time each day. Taking VYTORIN at the same time each day will have the best effect. It will also help you remember when to take your dose.

Your doctor may ask you to take VYTORIN with other cholesterol lowering agents such as bile acid sequestrants.

If you are taking a bile acid sequestrant, such as cholestyramine, take your VYTORIN either at least two hours before or four hours after taking the bile acid sequestrant.

How long to take it

VYTORIN helps lower your cholesterol. It does not cure your condition.

Therefore, you must continue to take it as directed by your doctor if you expect to lower your cholesterol and keep it down.

You may have to take cholesterol lowering medicine for the rest of your life. If you stop taking VYTORIN, your cholesterol levels may rise again.

If you forget to take it

If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to. Otherwise, take it as soon as you remember, and then go back to taking your tablet as you would normally.

If you are not sure whether to skip the dose, talk to your doctor or pharmacist.

Do not take a double dose to make up for the dose that you missed.

If you have trouble remembering to take your tablet, ask your pharmacist for some hints.

If you take too much (overdose)

Immediately telephone your doctor or Poisons Information Centre (telephone 13 11 26), or go to accident and emergency at your nearest hospital, if you think that you or anyone else may have taken too much VYTORIN. Do this even if there are no signs of discomfort or poisoning.

While you are using VYTORIN

Things you must do

If you become pregnant while taking VYTORIN, stop taking it and tell your doctor immediately.

Have your blood fats checked when your doctor says, to make sure VYTORIN is working. Even if you are taking medicines to treat high cholesterol, it is important to have your cholesterol measured regularly. You should also know your cholesterol levels and goals.

If you are about to be started on any new medicine, tell your doctor and pharmacist that you are taking VYTORIN.

If you are about to have elective surgery, tell your doctor that you are taking VYTORIN. Your doctor may suggest stopping the tablets a few days before surgery.

Things you must not do

Do not give VYTORIN to anyone else, even if they have the same condition as you.

Things to be careful of

Avoid drinking large quantities of alcohol. Drinking large quantities of alcohol may increase your chance of VYTORIN causing liver problems.

Avoid drinking large quantities of grapefruit juice. Grapefruit juice contains one or more components that alter the metabolism of some medicines, including VYTORIN. Therefore, drinking very large quantities (over 1 litre) of grapefruit juice each day increases your chance of VYTORIN causing side effects. These include aching muscles, muscle tenderness or weakness, not caused by exercise. However, one glass (250mL) of grapefruit juice each day has not been shown to have any significant effect.

Be careful driving or operating machinery until you know how VYTORIN affects you. There have been side effects reported with VYTORIN that may affect your ability to drive or operate machinery. Individual responses to VYTORIN may vary.

High cholesterol can be treated in two main ways:

Lifestyle Changes -
this includes a cholesterol-lowering diet, increasing physical activity, and weight management. Ask your doctor for advice before increasing physical activity.

Medicines -
cholesterol-lowering medicines are used together with lifestyle changes to help lower cholesterol.

Side Effects

Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking VYTORIN. VYTORIN helps most people with high cholesterol, but it may have unwanted side effects in a few people. All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.

Ask your doctor or pharmacist to answer any questions you may have.

Tell your doctor immediately or go to accident and emergency at your nearest hospital, if you notice any of the following:
swelling of the face, lips, mouth, throat or tongue which may cause difficulty in swallowing or breathing

These are serious side effects. If you have them, you may have had a serious allergic reaction to VYTORIN. You may need urgent medical attention or hospitalisation. Serious side effects are rare.

Tell your doctor immediately if you notice any of the following:
skin rash and hives
dark coloured urine
light coloured bowel motions
yellowing of the skin and eyes
joint pain
bleeding or bruising more easily than normal
steady abdominal pain with nausea and vomiting.

These may be serious side effects. You may need urgent medical attention. Serious side effects are rare.

Tell your doctor immediately if you notice the following:
unexplained muscle aches, tenderness or weakness, not caused by exercise.

This may be a serious side effect. This is because on rare occasions, muscle problems can be serious, including muscle breakdown resulting in kidney damage. You may need urgent medical attention.

Serious side effects are rare.

Other side effects not listed above may also occur in some patients. Tell you doctor if you notice any other effects.

Tell your doctor if you notice any of the following:
Unusual tiredness or weakness
Muscle aches

These are the more common side effects of VYTORIN or of either ezetimibe or simvastatin.

Tell your doctor if you notice any of the following:
Tingling or numbness of the hands or feet
Trouble sleeping
Poor memory

These are rare side effects of ezetimibe.

Do not be alarmed by these lists of possible side effects. You may not experience any of them.

After using VYTORIN


Keep your tablets in the blister pack until it is time to take them. If you take the tablets out of the blister pack they may not keep well.

Keep VYTORIN in a cool dry place where the temperature stays below 25 °C. Do not store it or any other medicine in the bathroom or near a sink.

Do not leave it in the car or on window sills. Heat and dampness can destroy some medicines.

Keep it where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.


If your doctor tells you to stop taking VYTORIN or the tablets have passed their expiry date, ask your pharmacist what to do with any that are left over.

Product description

What it looks like

VYTORIN comes in four types of tablets:
VYTORIN 10/10 - 10mg Ezetimibe/10mg Simvastatin: White to off-white, capsule shaped, biconvex compressed tablet marked with "311". [Not available in Australia]
VYTORIN 10/20 - 10mg Ezetimibe/ 20mg Simvastatin: White to off-white, capsule shaped, biconvex compressed tablet marked with "312".
VYTORIN 10/40 - 10mg Ezetimibe/ 40mg Simvastatin: White to off-white, capsule shaped, biconvex compressed tablet marked with "313".
VYTORIN 10/80 - 10mg Ezetimibe/ 80mg Simvastatin: White to off-white, capsule shaped, biconvex compressed tablet marked with "315".

A starter pack of VYTORIN contains 5 or 10 tablets. A trade pack contains 30 tablets.


Active ingredient:

VYTORIN 10/10 -
10mg ezetimibe/10mg simvastatin per tablet

VYTORIN 10/20 -
10mg ezetimibe/20mg simvastatin per tablet

VYTORIN 10/40 -
10mg ezetimibe/ 40mg simvastatin per tablet

VYTORIN 10/80 -
10mg ezetimibe/ 80mg simvastatin per tablet

Inactive ingredients:
butylated hydroxyanisole
citric acid monohydrate
croscarmellose sodium
magnesium stearate
microcrystalline cellulose
propyl gallate

VYTORIN does not contain gluten, sucrose, tartrazine or any other azo dyes.


VYTORIN is supplied in Australia by:
Merck Sharp & Dohme (Australia) Pty Limited
A.B.N 14000 173 508
54-68 Ferndell Street

Schering-Plough Pty Limited
A.B.N 570 002 352 45
Level 4, 66 Waterloo Road
North Ryde NSW 2113

This leaflet was prepared in July 2008.

This CMI leaflet was current at the time of printing. To check if it has been updated, please view our website, www.vytorin.com.au, or ask your pharmacist.

Australian Register Number:

VYTORIN 10/10 - AUST R 98100
VYTORIN 10/20 - AUST R 98111
VYTORIN 10/40 - AUST R 98115
VYTORIN 10/80 - AUST R 98117


® Registered Trademark of MSP Singapore Company LLC

Preferred Generic
Our preferred generic for this medication is listed below. A generic prescription medicine works in the same way as the existing medicine. What matters is the active ingredient, which is the same in the generic brands and the existing brand. Please click on it below to view the product(s).
Enalapril Sandoz 20mg Tablets 30
Enalapril Sandoz 20mg Tablets 90 (3 x 30) (Authority Script)
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Alternative Product(s)
There is generic brand to choose from in the table below. Generic Brands are less expensive brands that have been proven to have the same effect. Please select the desired brand.* *Some Doctor's will have "no substitution permitted" endorsed on the script. Please check your prescription as generics are not available in this case.
Enalapril Sandoz 20mg Tablets 30
Enalapril Sandoz 20mg Tablets 90 (3 x 30) (Authority Script)
Renitec 20mg Tablets 60 (2 x 30) (Authority Script)