contains the active ingredient nifedipine
Consumer Medicine Information
What is in this leaflet
This leaflet answers some common questions about ADDOS XR.
It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist.
All medicines have benefits and risks. Your doctor has weighed the risks of you taking ADDOS XR against the benefits they expect it will have for you.
If you have any concerns about taking this medicine, talk to your doctor or pharmacist.
Keep this leaflet with your medicine. You may need to read it again.
What ADDOS XR is used for
ADDOS XR is used either to treat high blood pressure or to prevent chronic stable angina, one of a number of types of angina.
ADDOS XR is not used for the relief of a sudden attack of angina.
ADDOS XR belongs to a group of medicines called calcium channel blockers. They work by opening up blood vessels in the body to lower blood pressure and improve the supply of blood and oxygen to the heart.
Your doctor may have prescribed ADDOS XR for another reason. Ask your doctor if you have any questions about why ADDOS XR has been prescribed for you.
ADDOS XR is specially designed to allow the slow release of the active substance from the tablet after it is taken. It is composed of a strong outer shell which does not dissolve in the body and is excreted in the faeces. It is normal to find these "tablet shells" in the faeces. The active substance contained in them has been absorbed by the body before excretion.
ADDOS XR is available only with a doctor's prescription.
Before you take ADDOS XR
When you must not take it
Do not take ADDOS XR if you are allergic to:
other calcium channel blockers such as amlodipine, felodipine or israldipine
any of the ingredients listed at the end of this leaflet.
Some of the symptoms of an allergic reaction may include skin rash, itching or hives, swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing, wheezing or shortness of breath.
Do not take ADDOS XR if you are taking another medicine containing rifampicin e.g. Rifadin, Rimycin.
Do not take ADDOS XR if you are pregnant. ADDOS XR may affect your developing baby if you take it during pregnancy.
Do not take ADDOS XR if you are breastfeeding. ADDOS XR passes into breast milk and may affect your baby.
Do not take ADDOS XR if the expiry date (Exp.) printed on the pack has passed. It may not work as well if you do.
Do not take ADDOS XR if the packaging shows signs of tampering or the tablets do not look quite right.
Before you start to take it
Tell your doctor if you are allergic to any other medicines, foods, dyes or preservatives.
Tell your doctor if you plan to become pregnant.
Tell your doctor if you have, or have had, any medical conditions, especially the following:
narrowing of the aorta
blockage of your oesophagus or bowel
surgery on your bowel.
If you have not told your doctor about any of the above, tell them before you start taking ADDOS XR.
Taking other medicines
Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop.
Some medicines may be affected by ADDOS XR, or may affect how well it works. These include:
cimetidine, a medicine commonly used to treat reflux and ulcers
warfarin, a medicine used to treat and prevent blood clots
some medicines used to treat high blood pressure
digoxin, a medicine used to treat certain heart conditions
quinidine, a medicine used to treat heart problems
phenytoin, a medicine used to treat epilepsy.
Your doctor can tell you what to do if you are taking any of these medicines.
If you are not sure whether you are taking any of these medicines, check with your doctor or pharmacist.
Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking ADDOS XR.
You should not eat grapefruit or drink grapefruit juice while you are taking ADDOS XR because this may affect how well the tablets work.
How to take ADDOS XR
How much to take
The dose varies from patient to patient.
The usual starting dose is 30 mg or one tablet per day. Your doctor may increase the dose slowly over several weeks depending on how you respond to this medicine.
Follow all directions given to you by your doctor and pharmacist carefully.
How to take ADDOS XR
Swallow the tablets whole with a glass of liquid. ADDOS XR should not be chewed or broken up.
If you forget to take ADDOS XR
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to.
Otherwise, take the missed dose as soon as you remember (if less than 12 hours to the next dose), and then go back to taking your tablets as you would normally.
Do not take more than one dose at a time to make up for the dose you missed.
If you are not sure what to do, ask your doctor or pharmacist.
How long to take ADDOS XR for
ADDOS XR helps control your condition, but does not cure it. Therefore you must take it every day. Continue taking your tablets for as long as your doctor tells you to.
Do not stop taking the tablets suddenly unless your doctor tells you to. You may suffer unwanted effects if you stop taking this medicine suddenly.
If you take too much ADDOS XR (overdose)
Immediately telephone your doctor, or the Poisons Information Centre (telephone 13 11 26), or go to Accident and Emergency at the nearest hospital, if you think you or anyone else may have taken too much ADDOS XR. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.
Symptoms of overdosage may include feeling dizzy and fainting due to a drop in blood pressure, irregular or rapid heart beats, shortness of breath and even loss of consciousness.
While you are taking ADDOS XR
Things you must do
Take ADDOS XR exactly as your doctor has prescribed. If you do not follow your doctor's instructions, you may not get control of your blood pressure or relief from your angina.
Tell your doctor if you continue to have angina attacks or if they become more frequent while you are taking ADDOS XR.
Before starting any new medicine, tell your doctor or pharmacist that you are taking ADDOS XR.
Tell all the doctors, dentists and pharmacists who are treating you that you are taking ADDOS XR.
If you become pregnant while taking ADDOS XR, tell your doctor immediately.
Things you must not do
Do not use ADDOS XR to treat any other conditions unless your doctor tells you to.
Do not give ADDOS XR to anyone else, even if they have the same condition as you.
Things to be careful of
Be careful driving or operating machinery until you know how ADDOS XR affects you. ADDOS XR may cause dizziness, light-headedness, fainting, or visual disturbances in some patients, especially when they first start taking the medicine. Make sure you know how you react to ADDOS XR before driving a car, operating machinery, or doing anything else that could be dangerous if you are affected.
If you feel light-headed, dizzy or faint when getting out of bed or standing up, get up slowly. This may be more noticeable when you first start taking ADDOS XR.
Standing up slowly, especially when you get up from lying down or sitting, will help your body get used to the change in position and blood pressure. If this problem continues or gets worse, talk to your doctor.
If you are a man participating in an in vitro fertilisation program, ADDOS XR may affect the likelihood of success. Speak to your doctor if you are concerned about this.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking ADDOS XR. ADDOS XR helps most people with high blood pressure or chronic stable angina, but it may have unwanted side effects in some people.
All medicines have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.
Do not be alarmed by this list of possible side effects. You may not experience any of them.
Ask your doctor or pharmacist to answer any questions you may have.
Tell your doctor if you notice any of the following and they worry you:
dizziness or light-headedness
feeling sick, vomiting, heartburn, indigestion or diarrhoea
These are the more common side effects of ADDOS XR. They are usually mild.
Tell your doctor immediately if you notice any of the following:
swelling of the ankles or legs
passing more or less urine than is usual for you
itching skin or rash
swelling of the breasts in men
These are serious side effects. You may need urgent medical attention. Serious side effects are rare.
If any of the following happen, either tell your doctor immediately or go to Accident and Emergency at your nearest hospital:
severe red scaly skin rash, hives
wheezing, difficulty breathing or shortness of breath
swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing
signs of worrying or frequent infections such as fever, severe chills, sore throat or mouth ulcers
yellowing of the skin and/or eyes
any unusual bleeding or bruising
fast or irregular heart beats
confusion and dizziness with visual and speech problems
These are very serious side effects. You may need urgent medical attention or hospitalisation. These side effects are rare.
Other side effects not listed above may also occur in some patients. Tell your doctor if you notice anything that is making you feel unwell.
After using ADDOS XR
Keep ADDOS XR where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
Keep your tablets in a cool dry place where the temperature stays below 25°C.
Do not store ADDOS XR or any other medicine in the bathroom or near a sink.
Do not leave ADDOS XR in the car or on window sills. Heat and dampness can destroy some medicines.
Keep the tablets in their blister pack until it is time to take them. If you take the tablets out of the box or the blister pack they may not keep well.
If your doctor tells you to stop taking ADDOS XR, or your tablets have passed their expiry date, ask your pharmacist what to do with any that are left over.
What it looks like
ADDOS XR comes in 2 strengths of tablets:
ADDOS XR 30 - round, pale red tablet marked "30" on one side.
ADDOS XR 60 - round pale red tablet marked "60" on one side.
Each blister pack contains 30 tablets.
The active ingredient in ADDOS XR is nifedipine.
each ADDOS XR 30 tablet contains 30 mg of nifedipine
each ADDOS XR 60 tablet contains 60 mg of nifedipine
The tablets also contain:
colloidal anhydrous silica
titanium dioxide (171)
iron oxide red CI77491
The tablets are gluten free.
ADDOS XR is supplied by:
Arrow Pharmaceuticals Limited
24 Rothschild Ave
Rosebery NSW 2018
Australian registration numbers:
ADDOS XR 30: Aust R 114825
ADDOS XR 60: Aust R 98806
Date of preparation:
ADDOS XR/012005/CMI-1 3
Published by MIMS/myDr August 2005
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