Zarontin 250mg/5mL Syrup 200mL


Drug Name: ethosuximide
Our Price $24.39
PBS $0.00
Concession $5.20
Safety Net $0.00

S8 Note - This prescription item is Schedule 8 and can only be supplied on a script from a registered doctor in Queensland. Any prescriptions from any other state cannot be filled and will be returned in the mail

Note: Private, PBS and our prices are available to the general public. Concession and Safety Net prices are only available to people with the appropriate concession or Safety Net cards. See Prescriptions for more details.


This prescription item requires a pre approved authority from the Government in order to get this item at the quoted price. Authority prescriptions need to be applied for by the doctor writing the script and can include reasons such as increased quantities due to dosage, increased repeats, use for a pre determined specified use, or the nature of the medication itself requiring specialist interaction. In the event that an authority is not granted on the script, the price will revert to the private price quoted for that item


This item contains more than one pack of a prescription product. Before this can be dispensed the doctor has to give approval. The prescription must be written for the total quantity or the prescription must be endorsed by your doctor "Regulation 24" otherwise we will be unable to dispense the increased amount. If you proceed with the order without approval, we will only send out one pack at the single pack price and refund the difference. Eg If your prescription is written out for 30 Tablets with 5 repeats and it does not have “Regulation 24 “ written on the script, the ONLY quantity we can dispense is 30 at one time. Further dispensing of this product could only occur after an appropriate length of time - usually 21 days but depends on dosage. In this example if you would like to obtain 180 Tablets then the doctor must endorse the prescription “Regulation 24” or the quantity must be written out for 180 and not 30. NB Conditions apply on the writing of a Regulation 24 prescription. Ask your doctor or pharmacist for details.

We can no longer accept signed authority forms from your doctor as permission to dispense more than one pack. Please contact our pharmacist for more information.

If you order this item as Private, NO PBS stickers will be issued. Once any prescription order has been sent the product cannot be returned for a refund even if your doctor changes your medication or you have an adverse reaction.

Zarontin 250mg/5mL Syrup 200mL

Zarontin 250mg/5mL Syrup 200mL

Product ID: 61940

Pharmacist Only Medicine

This product is a Pharmacist Only Medicine and requires pharmacist advice before we can dispatch this product. You must first place the order and then contact our pharmacists within 48 hours on 1300 367 283. The pharmacist will determine if this product is appropriate for you and if so, approve the order. In the event that you do not do this, the product will be deleted from your order and the balance of your order will be dispatched. This is not required if you have a doctor's prescription.


General Information


Consumer Medicine Information

What is in this leaflet
This leaflet answers some common questions about Zarontin.

It does not contain all the available information.

It does not take the place of talking to your doctor or pharmacist.

All medicines have risks and benefits. Your doctor has weighed the risks of you or your child taking Zarontin against the benefits they expect it will have for you.

If you have any concerns about taking this medicine, ask your doctor or pharmacist.

Keep this leaflet with the medicine. You may need to read it again.

What Zarontin is used for
Zarontin is used to control epilepsy in children and adults. Epilepsy is a condition where you have repeated seizures (fits). There are many different types of seizures, ranging from mild to severe.

Zarontin is used to control petit mal seizures.

Zarontin belongs to a group of medicines called anticonvulsants. These drugs are thought to work by controlling brain chemicals which send signals to nerves so that seizures do not happen.

Zarontin may be used alone, or in combination with other medicines, to treat your condition.

Your doctor may have prescribed Zarontin for another reason. Ask your doctor if you have any questions about why Zarontin has been prescribed for you.

There is no evidence that Zarontin is addictive.

This medicine is available only with a doctor's prescription.

Before you take Zarontin
When you must not take it
Do not take Zarontin if you have an allergy to ethosuximide, the active ingredient in Zarontin, other succinimides or any of the ingredients listed at the end of this leaflet.

Symptoms of an allergic reaction to Zarontin may include:

shortness of breath, wheezing or difficulty breathing
swelling of the face, lips, tongue or other parts of the body
rash, itching or hives on the skin
Do not take Zarontin after the expiry date (EXP) printed on the pack.

Do not take Zarontin if the packaging is torn or shows signs of tampering.

If it has expired or is damaged, return it to your pharmacist for disposal.

If you are not sure whether you should start taking Zarontin, talk to your doctor or pharmacist.

Before you start to take it
Tell your doctor or pharmacist if you have allergies to:

any other medicines, especially barbiturates or any other anticonvulsant medicines
any other substances, such as foods, preservatives or dyes
Tell your doctor if you have or have had any medical conditions, especially the following:

liver problems
kidney problems
Systemic Lupus Erythematosus
frequent infections such as fever, chills, sore throat or mouth ulcers
Tell your doctor if you are pregnant or intend to become pregnant. If it is necessary for you to take Zarontin, your doctor can help you decide whether or not to take it during pregnancy. Zarontin may affect your developing baby if you take it during pregnancy. However,it is very important to control your fits while you are pregnant.

Tell your doctor if you are breast-feeding or plan to breast-feed. Your doctor will discuss the possible risks and benefits of using Zarontin during breastfeeding.

If you do breastfeed, watch your baby carefully. If your baby develops a skin rash, becomes sleepy or has unusual symptoms, don't breastfeed again until you speak to your doctor.

If you have not told your doctor or pharmacist about any of the above, tell them before you start taking Zarontin.

Taking other medicines
Tell your doctor or pharmacist if you are taking any other medicines, including any that you buy without a prescription from your pharmacy, supermarket or health food shop. Some medicines and Zarontin may interfere with each other. These include other medicines used to treat fits and convulsions, such as phenytoin and valproic acid.

These medicines may be affected by Zarontin, or may affect how well it works. You may need different amounts of your medicine, or you may need to take different medicines. Your doctor or pharmacist will advise you.

Your doctor and pharmacist may have more information on medicines to be careful with or avoid while taking Zarontin.

How to take Zarontin
How much to take
Your doctor will tell you how much syrup or how many capsules you will need to take each day. This may depend on your age, the severity of your condition and whether or not you are taking any other medicines.

Your doctor may recommend that you start with a low dose of Zarontin and slowly increase the dose to the lowest amount needed to control your epilepsy/convulsions.

Follow all directions given to you by your doctor carefully. They may differ from the information contained in this leaflet.

If you do not understand the instructions on the bottle, ask your doctor or pharmacist for help.

How to take it
If you are taking Zarontin capsules

Swallow Zarontin capsules whole with a full glass of water.

If you or your child are taking Zarontin syrup

Shake the bottle well and accurately pour the dose with a medicine measure before taking it.

Shaking the bottle and using a medicine measure will make sure that you get the correct dose. You can geta medicine measure from your pharmacist. Ask your pharmacist for ways to accurately measure the dose.

When to take it
Take the daily dose of Zarontin in two divided doses.

Take Zarontin at about the same time each day. Taking Zarontin at the same time each day will have the best effect. It will also help you remember when to take the capsules or syrup.

It does not matter if you take Zarontin before or after food.

If you forget to take it
If it is almost time for your next dose (within 4 hours), skip the dose you missed and take your next dose when you are meant to.

Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally.

Do not take a double dose to make up for the dose that you missed. This may increase the chance of you getting an unwanted side effect.

If you are not sure what to do, ask your doctor or pharmacist.

If you have trouble remembering to take your medicine, ask your pharmacist for some hints.

How long to take it
Continue taking Zarontin for as long as your doctor tells you to. Zarontin helps control your condition, but does not cure it. Therefore you must take your medicine every day, even if you feel well.

Do not stop taking Zarontin, or lower the dosage, without checking with your doctor. Do not let yourself run out of medicine over the weekend or on holidays. Stopping Zarontin suddenly may cause unwanted effects or make your condition worse. Your doctor will slowly reduce your dose before you can stop taking it completely.

If you take too much (overdose)

Immediately telephone your doctor or the Poisons Information Centre (in Australia telephone 13 11 26; in New Zealand telephone 0800 POISON or 0800 764 766 0800 764 766), or go to Accident and Emergency at your nearest hospital, if you think that you or anyone else may have taken too much Zarontin. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.

While you are using Zarontin
Things you must do
Tell your doctor immediately if you notice any of the following:

increase in seizures (fits)
yellowing of the skin and/or eyes
swelling of the face
strong stomach pains
generally feeling unwell with tiredness, weakness and vomiting
These symptoms may mean that you have a serious condition affecting

your liver. You may need urgent medical attention.

Tell your doctor immediately if you have any thoughts about suicide or self-harm, any unusual changes in mood or behaviour, or you show signs of depression. Some people being treated with anti-epileptics such as Zarontin have thoughts of harming or killing themselves.

Patients and caregivers should be alert and monitor for these effects.

Signs and symptoms of suicide include:

thoughts or talk of death or suicide.
thoughts or talk of self-harm or harm to others
any recent attempts of self-harm
increase in aggressive behaviour, irritability or agitation
feelings of depression
Mention of suicide or violence must be taken seriously.

If you or someone you know is demonstrating these warning signs of suicide while taking Zarontin, contact your doctor or a mental health professional right away.

Tell any other doctors, dentists, and pharmacists who are treating you that you are taking Zarontin.

If you are about to be started on any new medicine, tell your doctor, dentist or pharmacist that you are taking Zarontin.

If you become pregnant while taking Zarontin, tell your doctor.

Tell your doctor if you are breast-feeding or plan to breast-feed.

If you do breastfeed, watch your baby carefully.

Before you have any surgery or emergency treatment, tell your doctor or dentist that you are taking Zarontin.

Tell your doctor if you feel Zarontin is not helping your condition. Your doctor may need to change your medicine.

Tell your doctor if, for any reason, you have not taken Zarontin exactly as prescribed. Otherwise, your doctor may change your treatment unnecessarily.

Be sure to keep all of your doctor's appointments so that your progress can be checked. Your doctor will check your progress and may want to take some tests from time to time. This helps to prevent unwanted side effects.

Things you must not do
Do not give Zarontin to anyone else, even if their symptoms seem similar to yours or they have the same condition as you.

Do not take Zarontin to treat any other complaints unless your doctor tells you to.

Do not stop using it unless your doctor tells you to.

Things to be careful of
Be careful driving or operating machinery until you know how Zarontin affects you. As with other anticonvulsant medicines, Zarontin may cause dizziness, light-headedness, tiredness, and drowsiness in some people. Make sure you know how you react to Zarontin before you drive a car, operate machinery, or do anything else that could be dangerous if you are dizzy or light-headed. If this occurs do not drive. If you drink alcohol, dizziness or light-headedness may be worse.

Children should not ride a bike, climb trees or do anything else that could be dangerous if they are feeling drowsy or sleepy. Zarontin may cause drowsiness, dizziness or sleepiness in some people and affect alertness.

Be careful when drinking alcohol while taking Zarontin. Combining Zarontin and alcohol can make you more sleepy, dizzy or lightheaded. Your doctor may suggest you avoid alcohol while you are being treated with Zarontin.

Side effects
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Zarontin. Zarontin helps most people with epilepsy, but it may have unwanted side effects in a few people. All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects. If you are over 65 years of age you may have an increased chance of getting side effects.

Ask your doctor or pharmacist to answer any questions you may have.

If you get any side effects, do not stop taking Zarontin without first talking to your doctor or pharmacist.

Tell your doctor or pharmacist if you notice any of the following and they worry you:

dizziness or light-headedness
feeling tired or drowsy
weakness, unsteadiness when walking
mood changes such as feelings of extreme happiness, irritability or excitement
loss of concentration
disturbance of sleep
frightening dreams
abnormally suspicious thoughts
increased libido
indigestion, stomach pain or discomfort
nausea (feeling sick) or vomiting
loss of appetite
loss of weight
swollen gums or tongue
itchy red skin rash or hives
excessive hairiness, especially in women
short sightedness
vaginal bleeding
allergic reaction
blood in the urine
These are the more common side effects of Zarontin. Mostly these are mild and short-lived.

Tell your doctor as soon as possible if you:

have any thoughts of suicide or self-harm
notice any unusual changes in your mood or behaviour
show signs of depression
Tell your doctor immediately or go to Accident and Emergency at your nearest hospital if you notice any of the following:

more frequent or more severe seizures (fits)
severe depression, apparent intentions of suicide
aggressive behaviour
frequent infections with fever, chills, sore throat, swollen glands and mouth ulcers
frequent nosebleeds, unusual bleeding or bruising,
tiredness, headache, shortness of breath when exercising, dizziness or pale skin
persistent nausea or vomiting, loss of appetite, generally feeling unwell, fever, itching, yellowing of the skin and/or eyes, dark coloured urine, light coloured bowel motions, pain in the abdomen. These may be signs of a liver problem.
sudden signs of allergy such as rash, itching or hives, swelling of the face, lips, wheezing or difficulty breathing
severe skin rash, itching, hives, blisters or peeling skin, which may be accompanied by fever, chills, headache, swollen glands, stomach pain or aching joints and muscles
severe whole body skin condition with severe blisters and bleeding in the lips, eyes, mouth, nose and genitals
These are very serious side effects. You may need urgent medical attention or hospitalisation.

All of these side effects are very rare.

Tell your doctor if you notice anything else that is making you feel unwell.

Do not be alarmed by this list of possible side effects. You may not experience any of them.

After using Zarontin
Keep your capsules in the pack until it is time to take them. If you take the capsules out of the pack they will not keep well.

Keep your capsules or syrup in a cool dry place where the temperature stays below 25 degrees C.

Do not store Zarontin or any other medicine in the bathroom or near a sink.

Do not leave it on a window sill or in the car on hot days. Heat and dampness can destroy some medicines.

Keep it where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

If your doctor or pharmacist tells you to stop taking Zarontin or the capsules or syrup have passed their expiry date, ask your pharmacist what to do with any that are left over.

Product description
What it looks like
Zarontin capsules 250 mg are clear orange soft gelatin capsules, available in bottles of 200 capsules.

Zarontin syrup is a clear yellow to pink solution, available in a 200 mL bottle.

Zarontin capsules contain:

Ethosuximide 250 mg as the active ingredient.

The capsules also contain:

macrogol 400
methyl hydroxybenzoate
propyl hydroxybenzoate
sunset yellow FCF
Zarontin Syrup contains:

Ethosuximide 250 mg/5 mL as the active ingredient.

The syrup also contains:

sodium citrate
sodium benzoate
saccharin sodium
imitation raspberry flavour
purified water
citric acid monohydrate
Zarontin is supplied in Australia by:
Pfizer Australia Pty Limited
ABN 50 008 422 348
38-42 Wharf Road
West Ryde NSW 2114
Toll Free number: 1800 675 229 1800 675 229

Zarontin is supplied in New Zealand by:
Pfizer New Zealand Ltd
PO Box 3998
Auckland, New Zealand.
Toll Free number: 0800 736 363 0800 736 363

Australian Registration Numbers:
250 mg capsules: AUST R 94175
250 mg/5 mL syrup: AUST R 79031

This leaflet was revised on 05 February 2009

© Pfizer Australia Pty Ltd

All rights reserved

Published by MIMS/myDr July 2009

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