Consumer Medicine Information
What is in this leaflet
This leaflet answers some common questions about Kinson.
It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist.
All medicines have benefits and risks. Your doctor has weighed the risks of you taking Kinson against the benefits expected for you.
If you have any concerns about taking this medicine, talk to your doctor or pharmacist.
Keep this leaflet with your medicine. You may need to read it again.
What Kinson is used for
Kinson is used to treat some of the symptoms of Parkinson's disease. This is a disease of the nervous system that mainly affects body movement. The three main symptoms are shaking (tremor), muscle stiffness and slow and unsteady movement.
Kinson is most helpful in improving slow movement and muscle stiffness. It can also be helpful in treating shaking, difficulty in swallowing, drooling and unstable posture.
Parkinson's disease is caused by the brain not making enough of a chemical called dopamine. Dopamine helps the brain to control muscle movement.
Kinson contains two active ingredients, levodopa and carbidopa. Levodopa is a chemical closely related to dopamine which allows the body to make its own dopamine. Carbidopa makes sure that enough levodopa gets to the brain where it is needed. In many patients, Kinson reduces some of the symptoms of Parkinson's disease.
Kinson is not recommended for use in children under the age of 18, as its safety and effectiveness have not been established in this age group.
Ask your doctor if you have any questions about why Kinson has been prescribed for you. Your doctor may have prescribed Kinson for another reason.
Kinson is available only with a doctor's prescription.
Before you take Kinson
When you must not take it
Do not take Kinson if you are allergic to medicines containing levodopa, carbidopa or any of the ingredients listed at the end of this leaflet. Some of the symptoms of an allergic reaction may include skin rash, itching or hives; swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing; wheezing or shortness of breath.
Do not take Kinson if you have:
any unusual skin lumps or moles which have not been checked by your doctor
a history of melanoma (a type of skin cancer).
Do not take Kinson if you have a type of glaucoma called narrow-angle glaucoma.
Do not take Kinson if you are taking another medicine for depression called a monoamine oxidase inhibitor (MAOI), or you have previously taken a MAOI within the last 14 days. Some examples of MAOIs are phenelzine (Nardil) and tranylcypromine (Parnate).
Do not take Kinson if you are breastfeeding. It has been shown that one of the active ingredients of Kinson passes into breast milk. Therefore, because of the potential harm to the baby, Kinson should not be used during breastfeeding.
Do not take this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering.
If it has expired or is damaged, return it to your pharmacist for disposal.
If you are not sure whether you should start taking this medicine, talk to your doctor.
Before you start to take it
Tell your doctor if you are allergic to any other medicines, foods, dyes or preservatives.
Tell your doctor if you are pregnant or plan to become pregnant. Your doctor will discuss the risks and benefits of taking Kinson during pregnancy.
Tell your doctor if you wish to breastfeed.
Tell your doctor if you have, or have had, any medical conditions, especially the following:
depression, mental illness or psychiatric problems
uncontrollable twitching or jerking movements of the body
heart conditions, including irregular heart beat (arrhythmia)
lung conditions, including asthma
kidney or liver problems
convulsions or fits
stomach ulcer and/or duodenal ulcers (peptic ulcer)
high blood pressure.
Your doctor may want to take special care if you have any of these conditions.
Tell your doctor if you are currently taking levodopa or have taken it in the past. Some examples of medicines which contain levodopa are Madopar and Sinemet.
If you have not told your doctor about any of the above, tell them before you start taking Kinson.
Taking other medicines
Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop. Some medicines may be affected by Kinson, or may affect how well it works. These include:
selegiline (Eldepryl, Selgene), another medicine used to treat Parkinson's disease
medicines used to treat high blood pressure
some medicines used to treat depression
some medicines used to treat mental illness or psychiatric problems
phenytoin (Dilantin), a medicine used to treat convulsions
isoniazid, a medicine used to treat tuberculosis.
iron supplements and multivitamins containing iron
Your doctor can tell you what to do if you are taking any of these medicines.
If you are not sure whether you are taking any of these medicines, check with your doctor or pharmacist.
Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking Kinson.
How to take Kinson
Follow all directions given to you by your doctor and pharmacist carefully. They may differ from the information contained in this leaflet.
If you do not understand the instructions on the pack, ask your doctor or pharmacist.
How much to take
The dose varies from person to person.
The usual starting dose is one Kinson tablet three times a day. Your doctor may increase this dose depending on how you respond to this medicine whether or not you are taking any other medicines.
How to take Kinson
Swallow the tablets with a glass of water.
Kinson tablets can be divided in half along the breakline, if your doctor has prescribed half a tablet.
When to take Kinson
Take your medicine at about the same time each day. Taking it at the same time each day will have the best effect. It will also help you remember when to take it.
How long to take Kinson for
Keep taking Kinson for as long as your doctor recommends. Kinson helps control some of the symptoms of Parkinson's disease, but does not cure your condition. It is important that you take Kinson every day on a regular basis.
If you forget to take Kinson
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to.
Otherwise, take the missed dose as soon as you remember, and then go back to taking your tablets as you would normally.
Do not take a double dose to make up for the dose you missed.
If you are not sure what to do or have any questions, ask your doctor or pharmacist.
If you take too much Kinson (overdose)
Immediately telephone your doctor or the Poisons Information Centre (telephone 13 11 26) for advice, or go to Accident and Emergency at the nearest hospital, if you think you or anyone else may have taken too much Kinson. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.
While you are taking Kinson
Things you must do
Before starting any new medicine, tell your doctor or pharmacist that you are taking Kinson.
Tell all the doctors, dentists and pharmacists who are treating you that you are taking Kinson.
If you become pregnant while taking Kinson, tell your doctor.
If you plan to have surgery, including dental surgery, that needs a general anaesthetic, tell your doctor or dentist that you are taking Kinson.
If you are diabetic, check with your doctor or pharmacist before using urine sugar tests. Kinson may cause false test results with some urine sugar tests.
If you need to have any other blood or urine tests, tell your doctor that you are taking Kinson. Kinson may affect the results of some tests.
Visit your doctor regularly so they can check on your progress. You may need to have tests to check your blood, liver, kidneys and heart.
Tell your doctor if you feel Kinson is not working as well as it did previously.
In some people who have been taking Kinson for a long time, such as a year or more, sudden and unexpected losses of movement may occur.
These may last from a few minutes to several hours. Afterwards, the person can move as before. This is called the "on-off" effect. If this happens, your doctor may want to adjust your medicine.
Things you must not do
Do not stop taking Kinson, or lower the dose, without checking with your doctor. Stopping Kinson suddenly may cause muscle stiffness, fever and mental changes. Your doctor may want you to gradually reduce the amount of Kinson you are taking before stopping completely.
Do not use Kinson to treat any other conditions unless your doctor tells you to.
Do not give Kinson to anyone else, even if they have the same condition as you.
Things to be careful of
Do not drive or operate machinery until you know how Kinson affects you.
Kinson may cause dizziness, lightheadedness, sudden sleep onset episodes, or excessive drowsiness in some people. If any of these occur, do not drive, operate machinery or do anything else that could be dangerous.
Be careful getting up from a sitting or lying position.
Dizziness, lightheadedness or fainting may occur, especially when you get up quickly. This is because your blood pressure is suddenly falling. Getting up slowly may help. If this problem continues or gets worse, tell your doctor.
Be careful not to eat a diet high in protein.
The amount of levodopa absorbed by your body may be reduced if your diet is high in protein. Ask your doctor, pharmacist or dietician to check your diet.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Kinson. Kinson helps most people with Parkinson's disease, but it may have unwanted side effects in some people.
All medicines can have side effects.
Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.
Do not be alarmed by this list of possible side effects. You may not experience any of them.
Ask your doctor or pharmacist to answer any questions you may have.
Tell your doctor if you notice any of the following and they worry you:
abnormal uncontrolled movements including muscle twitching or spasms, which may or may not be like your Parkinson's symptoms
dizziness, lightheadedness when getting up quickly, fainting
nausea (feeling sick), vomiting, loss of appetite
constipation or diarrhoea
sudden episodes of sleep onset, excessive drowsiness
involuntary upward movement of the eyes.
For the most part, the above side effects have been mild.
Tell your doctor immediately if you notice any of the following:
skin rash, itching or hives
difficulty or pain in passing urine, blood in the urine
changes in mood such as depression
signs of anaemia such as tiredness, headaches, being short of breath when exercising, dizziness and looking pale
signs of frequent infections such as fever, severe chills, sore throat or mouth ulcers
bruising or bleeding more easily than normal
numbness or tingling in the hands or feet
The above list includes serious side effects which may require medical attention. Serious side effects are rare.
Tell your doctor immediately or go to Accident and Emergency at the nearest hospital if you notice any of the following:
swelling of the face, lips, mouth, tongue or throat which may cause difficulty in swallowing or breathing
difficulty breathing, wheezing or shortness of breath
bleeding from the back passage, black sticky bowel motions (stools) or bloody diarrhoea
vomiting blood or material that looks like coffee grounds
fast or irregular heart beats, also called palpitations
muscle stiffness accompanied by fever
mental changes such as feeling very fearful or paranoid, hallucinations
sudden increase in body temperature, muscular rigidity, tremors, extremely high blood pressure and severe convulsions
signs of melanoma, such as new skin spots, or changes to the size, shape, colour or edges of an existing skin spot, freckle or mole.
The above list includes very serious side effects. You may need urgent medical attention or hospitalisation. These side effects are very rare.
Other reported side effects include compulsive behaviours such as gambling (failure to resist gambling impulses despite serious personal or family consequences), increased sex drive and hypersexuality (altered sexual interest and behaviour of significant concern to the patient or to others), shopping, eating, medication use and repetitive purposeless activities.
These side effects occur mainly in patients treated with high doses of the medicine. They are usually reversible if the dose of the medicine is reduced or stopped.
Contact your doctor as soon as possible if you or someone you know is showing signs of unusual behaviour while taking Kinson.
Tell your doctor if you notice anything that is making you feel unwell. Other side effects not listed above may also occur in some patients. Some of these side effects can only be found when your doctor does tests from time to time to check your progress.
After taking Kinson
Keep Kinson where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
Keep your tablets in the bottle until it is time to take them. If you take the tablets out of the bottle they will not keep well.
Keep your tablets in a cool dry place where the temperature stays below 30 °C.
Do not store Kinson or any other medicine in the bathroom or near a sink.
Do not leave Kinson in the car or on window sills. Heat and dampness can destroy some medicines.
If your doctor tells you to stop taking Kinson, or your tablets have passed their expiry date, ask your pharmacist what to do with any that are left over.
What it looks like
Kinson is a round, yellow, scored tablet marked LC|2 on one side and a Greek alpha symbol on the other side.
Each bottle contains 100 tablets.
The active ingredients in Kinson are levodopa and carbidopa. Each Kinson tablet contains 100 mg of levodopa and 25 mg of carbidopa.
The tablets also contain the following inactive ingredients:
sodium starch glycollate
quinoline yellow CI 47005 (E104).
The tablets are gluten free.
Kinson is made in Australia by:
Alphapharm Pty Limited
(ABN 93 002 359 739)
Chase Building 2
Wentworth Park Road
Glebe NSW 2037
Phone: (02) 9298 3999
Phone: 1800 028 365
Australian registration number:
Kinson - AUST R 49481
This leaflet was prepared on 25 August 2008.