Clexane 100mg/mL Injection 10


Drug Name: enoxaparin sodium
Private Price $99.39
PBS $37.30
Concession $5.20
Safety Net $0.00

S8 Note - This prescription item is Schedule 8 and can only be supplied on a script from a registered doctor in Queensland. Any prescriptions from any other state cannot be filled and will be returned in the mail

Note: Private, PBS and our prices are available to the general public. Concession and Safety Net prices are only available to people with the appropriate concession or Safety Net cards. See Prescriptions for more details.


This prescription item requires a pre approved authority from the Government in order to get this item at the quoted price. Authority prescriptions need to be applied for by the doctor writing the script and can include reasons such as increased quantities due to dosage, increased repeats, use for a pre determined specified use, or the nature of the medication itself requiring specialist interaction. In the event that an authority is not granted on the script, the price will revert to the private price quoted for that item


This item contains more than one pack of a prescription product. Before this can be dispensed the doctor has to give approval. The prescription must be written for the total quantity or the prescription must be endorsed by your doctor "Regulation 24" otherwise we will be unable to dispense the increased amount. If you proceed with the order without approval, we will only send out one pack at the single pack price and refund the difference. Eg If your prescription is written out for 30 Tablets with 5 repeats and it does not have “Regulation 24 “ written on the script, the ONLY quantity we can dispense is 30 at one time. Further dispensing of this product could only occur after an appropriate length of time - usually 21 days but depends on dosage. In this example if you would like to obtain 180 Tablets then the doctor must endorse the prescription “Regulation 24” or the quantity must be written out for 180 and not 30. NB Conditions apply on the writing of a Regulation 24 prescription. Ask your doctor or pharmacist for details.

We can no longer accept signed authority forms from your doctor as permission to dispense more than one pack. Please contact our pharmacist for more information.

If you order this item as Private, NO PBS stickers will be issued. Once any prescription order has been sent the product cannot be returned for a refund even if your doctor changes your medication or you have an adverse reaction.

Clexane 100mg/mL Injection 10

Clexane 100mg/mL Injection 10

Product ID: 55690

Pharmacist Only Medicine

This product is a Pharmacist Only Medicine and requires pharmacist advice before we can dispatch this product. You must first place the order and then contact our pharmacists within 48 hours on 1300 367 283. The pharmacist will determine if this product is appropriate for you and if so, approve the order. In the event that you do not do this, the product will be deleted from your order and the balance of your order will be dispatched. This is not required if you have a doctor's prescription.


General Information

Consumer Medicine Information

What is in this leaflet

This leaflet answers some common questions about Clexane.

It does not contain all the available information.

It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you using Clexane against the benefits they expect it will have for you. If you have any concerns about using this medicine, ask your doctor or pharmacist.

Keep this leaflet with the medicine.

You may need to read it again. What Clexane is used for Clexane is used in a number of medical conditions. It is used to:
treat blood clots
treat certain types of heart disease (eg. angina and heart attacks), when used with aspirin
prevent blood clots forming after an operation, during hospitalisation or during purification of the blood by an artificial kidney (haemodialysis).

Clexane is one of a group of medicines called low molecular weight heparins (LMWH). These medicines work by reducing blood clotting activity. Your doctor may have prescribed Clexane for another reason. Ask your doctor if you have any questions about why Clexane has been prescribed for you.

There is no evidence that Clexane is addictive. This medicine is only available with a doctor's prescription. Before you are given Clexane When you must not be given it

Do not use Clexane if you have an allergy to Clexane, heparin or its derivatives including other LMWHs. Some signs and symptoms of an allergic reaction can include swelling of the face, lips or tongue, wheezing or troubled breathing, skin rash, itching hives, blisters or peeling skin.

Do not use Clexane if you have, or have ever had any of the following medical conditions:
major blood disorders
certain types of stroke
stomach or bowel problems such as ulcers or ulcerative colitis
bacterial infections in your heart.

Do not give Clexane to a child.

The safety and effectiveness of Clexane has not been established in children. Do not use Clexane after the expiry date printed on the syringe.

Do not use Clexane if the packaging is torn or shows signs of tampering.

If you are not sure whether you should start using Clexane, talk to your doctor or pharmacist.

Before you are given it

Tell your doctor or pharmacist if you have allergies to:
heparin or its derivatives, including other LMWHs
any other medicines
any other substances, such as foods, preservatives or dyes.

Tell your doctor or pharmacist if you have or have had any of the following medical conditions:
major bleeding disorder or blood clotting problem, including a recent stroke
stomach or bowel problems such as ulcers or ulcerative colitis
kidney or liver disease
uncontrolled high blood pressure
diabetic related eye disease
recently undergone brain or eye surgery
an artificial heart valve.

If you have not told your doctor or pharmacist about any of the above, tell them before you start using Clexane. Tell your doctor or pharmacist if you are pregnant or intend to become pregnant.

Like most LMWHs, Clexane is not recommended to be used during pregnancy. If there is a need to consider Clexane during your pregnancy, your doctor or pharmacist will discuss with you the benefits and risks of using it. Tell your doctor or pharmacist if you are breastfeeding or plan to breastfeed.

Like most LMWHs, Clexane is not recommended while you are breastfeeding. If there is a need to consider Clexane while you are breastfeeding, your doctor or pharmacist will discuss with you the benefits and risks of using it. Tell your doctor that you are using Clexane if your doctor is planning for you to have an anaesthetic injection in your back (spinal or epidural injection).

If you have not told your doctor or pharmacist about any of the above, tell them before you start using Clexane. Taking other medicines

Tell your doctor or pharmacist if you are taking any other medicines, including any that you buy without a prescription from your pharmacy, supermarket or health food shop.

Some medicines and Clexane may interfere with each other. These include:
medicines or substances used to prevent and treat blood clots
medicines containing aspirin or salicylates
Dextran 40, a medicine use to treat shock
medicines used to treat inflammatory disease, such as oral non-steroidal anti-inflammatory medicines or corticosteroids.

If any of these medicines are used while using Clexane, careful monitoring of your blood clotting factors is required by your doctor. These medicines may be affected by Clexane or may affect how well it works. You may need to use different amounts of your medicine or you may need to use different medicines. Your doctor or pharmacist will advise you. Your doctor and pharmacist may have more information on medicines to be careful with or avoid while using Clexane. How Clexane is given How much is given

Your doctor will decide what dose you will receive. This depends on your condition and other factors, such as your weight.

For the prevention of blood clots, the following are the usual doses, which are administered by injection under the skin once a day:
moderate risk patients: 20mg
high risk patients: 40mg

For the treatment of blood clots which have formed in the leg/deep vein, the usual dose is 1mg/kg body weight twice a day or 1.5mg/kg body weight once a day injected under the skin. Warfarin sodium therapy is usually started within 72 hours of Clexane by your doctor.

For patients that require dialysis, the usual dose is 1mg/kg into the tubing of the dialysis machine at the start of the session. Additional doses may be given if required. For treatment of certain types of heart disease, the usual dose is 1 mg/kg injected under the skin twice a day. These doses of Clexane may be changed by your doctor. Your doctor will decide when and how much Clexane you will be given. How to use it

Clexane is given by an injection under the skin or into the tubing of the dialysis machine. The recommended site for injection is the stomach area. A different injection site should be used for each injection. Do not rub the injection site after administration.

It may be given by your doctor, nurse or yourself. Your doctor will tell you how you will be given your injection. Prefilled Syringes

The prefilled syringes are ready for use. The air bubble in the syringe should not be expelled.

Graduated Prefilled Syringes

When using the 60mg, 80mg, 100mg, 120mg and 150mg graduated syringes, the volume to be injected should be measured precisely according to the dosage recommended by your doctor.

The whole length of the syringe needle should be introduced vertically into the thickness of a skin fold gently held between the operator's thumb and finger. This skin fold should be held throughout the duration of the injection. The syringes do not contain any antimicrobial agents, so must be used once only and any residue discarded. How long to use it

Your doctor will tell you how long you will be given Clexane.


As Clexane is usually given to you under the supervision of your doctor, it is very unlikely that you will receive too much. However, some patients may self-inject Clexane.

Tell your doctor or nurse or telephone the Poisons Information Centre in Australia (13 11 26) or the National Poisons Information Centre in NZ (0800 POISON or 0800 764 766), or go to Accident and Emergency at your nearest hospital, if you think that you or anyone else may have injected too much Clexane.

Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.

While you are using Clexane Things you must do

Use Clexane exactly as your doctor has prescribed.

If you become pregnant while using Clexane tell your doctor immediately.

Tell your doctor if you have an artificial heart valve.

If you are about to be started on any new medicine tell your doctor, dentist or pharmacist that you are using Clexane.

Tell any other doctors, dentists or pharmacists who are treating you that you are using Clexane.

If you plan to have surgery, tell your doctor or dentist that you are using Clexane.

Tell your doctor that you are using Clexane if your doctor is planning for you to have an anaesthetic injection in your back (spinal or epidural injection).

Things you must not do

Do not give Clexane to anyone else, even if they have the same condition as you.

Do not use Clexane to treat any other complaints, unless your doctor tells you to.

Do not stop using Clexane, or lower the dosage, without checking with your doctor or pharmacist.

Do not mix Clexane with other injections or infusion fluids.

Do not inject Clexane into a muscle.

Things to be careful of

Clexane is not interchangeable with other low molecular weight heparins (LMWH) products.

Ask you doctor whether there are any activities you should avoid while using Clexane, for example certain sports.

Sometimes after an injury bleeding may occur inside your body without you knowing about it. Be sure to keep all of your doctor appointments. Your doctor will check your progress and may want to take some blood tests from time to time. Side Effects Tell your doctor or pharmacist as soon as possible if you do not feel well while you are using Clexane.

All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects. Ask your doctor or pharmacist to answer any questions you may have.

Tell your doctor if you notice any of the following and they worry you:
Pain, bruising or irritation at the injection site after Clexane has been given
hard inflamed nodules at the injection site
itchy red rash at the injection site

If any of the following happen, stop using Clexane and tell your doctor immediately or go to the Emergency Department at your nearest hospital:
painful itchy red/purple rash at the injection site
difficulty in breathing, symptoms of hayfever, feeling faint or other symptoms of allergy
significant bleeding
severe abdominal, chest pain and headache.

If you need to have had an anaesthetic injection in your back (spinal or epidural injection) while taking Clexane, this should be done in a hospital. Tell your doctor immediately if any of the following happen after an anaesthetic injection in your back:
pain in the middle of your back (midline back pain)
numbness and weakness in your legs (sensory and motor deficits)
intestinal problems and problems in passing urine
a fine widespread rash, especially noticeable on your mouth or eyes or sudden onset of white or blue colour in fingers or toes suggesting poor blood supply.

These are very serious side effects. You may need urgent medical attention or hospitalisation. These side effects are rare. Other side effects not listed above may occur in some patients. Tell your doctor or pharmacist if you notice anything else that is making you feel unwell.

Do not be alarmed by this list of possible side effects. You may not experience any of them. After using Clexane If you have any queries about any aspect of your medicine, or any questions regarding the information in this leaflet, discuss them with your doctor or pharmacist.


Keep Clexane in a cool dry place where the temperature stays below 25 °C.

Keep the syringes in the pack until it is time to use them.

Do not freeze Clexane.

Do not leave Clexane in the car.

Keep Clexane away from direct sunlight.

Do not store Clexane or any other medicine in the bathroom, near a sink or stove or on a windowsill.

Heat, light and dampness can destroy some medicines. Keep Clexane where children cannot reach it.

A locked cupboard at least one and a half metres above the ground is a good place to store medicines. Disposal

If your doctor tells you to stop using Clexane or you find that the syringes have passed their expiry date, ask your doctor or pharmacist what to do with any that are left over.

Return any unused medicine to your pharmacist.

Product description What Clexane looks like

Clexane is available in the following range of presentations:

Ready to use Prefilled Syringes:
20mg/0.2mL, 10's
40mg/0.4mL, 10's

Ready to use Prefilled Syringes with graduated markings:
60mg/0.6mL, 10's
80mg/0.8mL, 10's
100mg/1.0mL, 10's
120mg/0.8mL, 10's
150mg/1.0mL, 10's


Active Ingredient:

Clexane contains enoxaparin sodium. Inactive Ingredients: Clexane also contains water for injections. Supplier
sanofi-aventis australia pty ltd
12-24 Talavera Road
Macquarie Park NSW 2113
sanofi-aventis new zealand limited
Auckland, New Zealand

Australian Register Numbers
20mg-AUST R 42965
40mg-AUST R 42962
60mg-AUST R 56709
80mg-AUST R 56710
100mg-AUST R 56711
120mg-AUST R 74173
150mg-AUST R 74175

This leaflet was prepared in October 2007.

® Registered Trademark * Subsequent references to "CLEXANE" refer to both CLEXANE and CLEXANE FORTE
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