Adefin 10mg Tablets 60


Drug Name: nifedipine
Our Price $8.99
PBS $17.16
Concession $5.20
Safety Net $0.00

S8 Note - This prescription item is Schedule 8 and can only be supplied on a script from a registered doctor in Queensland. Any prescriptions from any other state cannot be filled and will be returned in the mail

Note: Private, PBS and our prices are available to the general public. Concession and Safety Net prices are only available to people with the appropriate concession or Safety Net cards. See Prescriptions for more details.


This prescription item requires a pre approved authority from the Government in order to get this item at the quoted price. Authority prescriptions need to be applied for by the doctor writing the script and can include reasons such as increased quantities due to dosage, increased repeats, use for a pre determined specified use, or the nature of the medication itself requiring specialist interaction. In the event that an authority is not granted on the script, the price will revert to the private price quoted for that item


This item contains more than one pack of a prescription product. Before this can be dispensed the doctor has to give approval. The prescription must be written for the total quantity or the prescription must be endorsed by your doctor "Regulation 24" otherwise we will be unable to dispense the increased amount. If you proceed with the order without approval, we will only send out one pack at the single pack price and refund the difference. Eg If your prescription is written out for 30 Tablets with 5 repeats and it does not have “Regulation 24 “ written on the script, the ONLY quantity we can dispense is 30 at one time. Further dispensing of this product could only occur after an appropriate length of time - usually 21 days but depends on dosage. In this example if you would like to obtain 180 Tablets then the doctor must endorse the prescription “Regulation 24” or the quantity must be written out for 180 and not 30. NB Conditions apply on the writing of a Regulation 24 prescription. Ask your doctor or pharmacist for details.

We can no longer accept signed authority forms from your doctor as permission to dispense more than one pack. Please contact our pharmacist for more information.

If you order this item as Private, NO PBS stickers will be issued. Once any prescription order has been sent the product cannot be returned for a refund even if your doctor changes your medication or you have an adverse reaction.

Adefin 10mg Tablets 60

Adefin 10mg Tablets 60

Product ID: 55603

Pharmacist Only Medicine

This product is a Pharmacist Only Medicine and requires pharmacist advice before we can dispatch this product. You must first place the order and then contact our pharmacists within 48 hours on 1300 367 283. The pharmacist will determine if this product is appropriate for you and if so, approve the order. In the event that you do not do this, the product will be deleted from your order and the balance of your order will be dispatched. This is not required if you have a doctor's prescription.


General Information

Consumer Medicine Information

What is in this leaflet

This leaflet answers some common questions about Adefin 10 and Adefin 20 tablets (described below as Adefin tablets).

It does not take the place of talking to your doctor or pharmacist.

All medicines have risks and benefits. Your doctor has weighed the risks of you taking Adefin against the benefits expected for you. If you have any concerns about taking this medicine, talk to your doctor or pharmacist.

Keep this leaflet with your medicine. You may need to read it again.

The information supplied in this leaflet relates only to Adefin 10 and Adefin 20. It is not to be used in relation to any other product, which may also contain the same active ingredient. What Adefin is used for Adefin tablets are used either to treat high blood pressure or to prevent chronic stable angina (chest pain). Adefin tablets are not used for the relief of a sudden attack of angina. Adefin tablets contain the active substance nifedipine that belongs to a group of medicines called calcium channel blockers. They work by opening up blood vessels in the body to lower blood pressure and improve the supply of blood and oxygen to the heart. Ask your doctor if you have any questions about why Adefin have been prescribed for you. Your doctor may have prescribed Adefin for another reason.

Adefin is available only with a doctor's prescription. Before you take Adefin When you must not take it

Do not take Adefin if you are allergic to:
medicines containing nifedipine (eg. Adalat, Adefin XL)
medicines similar to nifedipine such as amlodipine (Norvasc), felodipine (eg. Plendil, Felodur), lercanidipine (Zanidip), nimodipine (Nimotop)
any of the ingredients listed at the end of this leaflet.

Some of the symptoms of an allergic reaction may include skin rash, itching or hives; swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing; wheezing or shortness of breath. Do not take Adefin if you are pregnant or plan to become pregnant. It may affect your developing baby if you take it during pregnancy.

Do not take Adefin if you are breastfeeding or plan to breastfeed. Adefin passes into breast milk and may affect your baby.

Do not take Adefin within eight days after a heart attack.

Do not take Adefin if you are in cardiogenic shock (very low blood pressure due to a failing heart).

Do not take Adefin if you are taking another medicine containing rifampicin (Rifadin, Rimycin).

Do not take Adefin after the expiry date (EXP) printed on the pack has passed. If you take this medicine after the expiry date, it may not work as well.

Do not take Adefin if the packaging shows signs of tampering or if the tablets do not look quite right.

If you are not sure whether you should start taking this medicine, talk to your doctor.

Before you start to take Adefin

Tell your doctor if you are allergic to any other medicines, foods, dyes or preservatives.

Tell your doctor if you have or have had any medical conditions, especially the following:
very low blood pressure
heart failure
narrowing of the aorta
liver problems

Tell your doctor if you plan to have surgery.

Tell your doctor if you intend to father children using the in vitro fertilisation method.

If you have not told your doctor about any of the above, tell him/her before you start taking Adefin.

Taking other medicines

Do not take Adefin if you are taking rifampicin (Rifadin, Rimycin).

Tell your doctor if you eat grapefruit or drink grapefruit juice before you start taking Adefin. Grapefruit juice can affect the blood pressure lowering effect of Adefin.

Tell your doctor if you are taking any other medicines, including those that you buy without a prescription from a pharmacy, supermarket or health food shop.

Some medicines may be affected by Adefin or may affect how well it works. These include:
cimetidine (eg. Tagamet, Magicul)
erythromycin (eg. EES, E-Mycin)
warfarin (Coumadin, Marevan)
digoxin (eg. Lanoxin)
certain medicines used to treat high blood pressure or angina such as diltiazem (eg. Cardizem, Coras), irbesartan (eg. Avapro), candesartan cilexetil (eg. Atacand)
quinidine (Kinidin)
phenytoin (eg. Dilantin), carbamazepine (eg. Tegretol, Teril), sodium valproate (Epilim, Valpro), phenobarbitone
cisapride (Prepulsid)
medicines taken to treat fungal infections such as ketoconazole (Nizoral), itraconazole (Sporanox), fluconazole (eg. Diflucan)
certain medicines taken for viral infections
tacrolimus (Prograf)
certain medicines used for asthma.

If you are not sure whether you are taking any of these medicines, check with your doctor or pharmacist. Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking Adefin.

How to take Adefin

Follow all directions given to you by your doctor and pharmacist carefully. They may differ from the information contained in this leaflet.

If you do not understand the instructions on the pack, ask your doctor or pharmacist.

How much to take

The dose may vary from person to person.

Your doctor will decide the right dose for you. This may depend on your condition, other medicines you are taking and how you respond to Adefin. The usual dosage is 10 mg to 20 mg twice daily. If required, your doctor may increase the dose up to 40 mg twice daily. The maximum dose of Adefin is 80 mg (daily). How to take Adefin

The tablets are to be swallowed with some liquid, with or without food.

When to take Adefin

The tablets are usually taken every 12 hours.

The tablets should generally be taken first thing in the morning, followed by the second dose before going to bed.

Take your medicine at about the same time each day. Taking it at the same time each day will have the best effect. It will also help you remember when to take it.

How long to take Adefin for

Keep taking Adefin for as long as your doctor recommends. Your doctor will determine how long you should take Adefin tablets.

This medicine helps to control your condition, but does not cure it. It is important to keep taking your medicine even if you feel well.

If you forget to take Adefin

If you have missed a dose by more than 6 hours, skip the dose you missed and take the next dose when you are meant to. Otherwise, take it as soon as you remember and then go back to taking your medicine as you would normally.

Do not take a double dose to make up for the dose that you missed. This may increase the chance of you getting an unwanted side effect.

If you have missed several doses, consult your doctor.

If you are not sure what to do or have any questions, ask your doctor or pharmacist.

If you take too much Adefin (overdose)

Immediately telephone your doctor, or the Poisons Information Centre (telephone 13 11 26), or go to Accident and Emergency at the nearest hospital, if you think you or anyone else may have taken too much Adefin.

Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.

Signs of an overdose include feeling dizzy and fainting due to drop in blood pressure, irregular heart beats, shortness of breath and even loss of consciousness. While you are taking Adefin Things you must do

Take Adefin tablets exactly as prescribed by your doctor. If you do not follow your doctor's instructions, you may not get control of your blood pressure or angina.

Tell your doctor immediately if you continue to have angina attacks or if they become more frequent while you are taking Adefin tablets.

If you become pregnant while taking Adefin, tell your doctor immediately.

If you are about to be started on any new medicine, remind your doctor and pharmacist that you are taking Adefin.

Tell all the doctors, dentists and pharmacists who are treating you that you are taking Adefin.

Things you must not do

Do not stop taking your medicine or lower the dosage without checking with your doctor.

Do not use Adefin to treat any other conditions unless your doctor tells you to.

Do not give Adefin to anyone else, even if they have the same symptoms as you.

Things to be careful of

Make sure you know how Adefin affects you before you drive a car, operate machinery, or do anything else that could be dangerous. Adefin tablets may cause dizziness or fainting in some people who have low blood pressure, especially when they first start taking the medicine, change dose or drink alcohol.

If you have angina, be careful not to overdo physical activities when you first start taking Adefin tablets. You may feel better when you start taking it, but you will need time to improve your physical fitness.

Side effects Tell your doctor or pharmacist as soon as possible if you do not feel well while taking Adefin. Adefin helps most people with high blood pressure or chronic stable angina. However, like other medicines, they may have unwanted effects in some people.

All medicines have side effects. Sometimes they are serious, most of the time they are not. You may need medical attention if you get some of these side effects. Do not be alarmed by this list of possible side effects. You may not experience any of them.

Ask your doctor or pharmacist to answer any questions you may have.

Tell your doctor if you notice any of the following and they worry you:
feeling dizzy
feeling sick (nausea)
unusual tiredness or weakness.

The above list includes the more common and mild side effects. Tell your doctor as soon as possible if you notice any of the following:
blurred vision
bleeding, tender or swollen gums
swelling of ankles, feet or lower leg
painful, swollen joints
rash or blistering of the skin when exposed to sunlight
unusual bleeding or bruising under the skin
passing more urine than normal
breast enlargement (in men)
signs of liver problems such as yellowing of the skin and/or eyes (jaundice)
signs of frequent infections such as fever, severe chills, sore throat or mouth ulcers.

The above list includes serious side effects, which may need medical attention. Tell your doctor immediately or go to Accident and Emergency at the nearest hospital if you notice any of the following:
fast or irregular heartbeat
chest pain
signs of an allergic reaction such as skin rash, itching or hives; swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing; wheezing or shortness of breath
flaking or peeling of the skin.

These are very serious side effects. You may need urgent medical attention or hospitalisation.

Tell your doctor if you notice anything that is making you feel unwell. This is not a complete list of all possible side effects.

Other side effects not listed above may also occur in some people. After taking Adefin Storage

Keep Adefin where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

Keep your tablets in the pack until it is time to take them. If you take the tablets out of the pack they will not keep well.

Keep your tablets in a cool dry place where the temperature stays below 25°C.

Do not store Adefin or any other medicine in the bathroom or near a sink.

Do not leave Adefin in the car or on window sills. Heat and dampness can destroy some medicines.


If your doctor tells you to stop taking Adefin or your tablets have passed their expiry date, ask your pharmacist what to do with any that are left over.

Product description What it looks like

Adefin tablets are available in two strengths:
Adefin 10 - round, film-coated pink-grey tablets marked with "A 10" on one side.
Adefin 20 - round, film-coated pink-grey tablets marked with "1 U" on one side and the Bayer cross on the other.

Each pack contains 60 tablets. Ingredients

The active ingredient in Adefin is nifedipine.

Each Adefin 10 tablet contains 10 mg of nifedipine.

Each Adefin 20 tablet contains 20 mg of nifedipine.

Adefin 10 and Adefin 20 tablets also contain the following inactive ingredients:
microcrystalline cellulose
maize starch
polysorbate 80
macrogol 4000
magnesium stearate
iron oxide red (CI77491)
titanium dioxide.


Adefin is supplied by:

Alphapharm Pty Limited
(ABN 93 002 359 739)
Chase Building 2
Wentworth Park Road
Glebe NSW 2037

Phone: (02) 9298 3999
Medical Information

Phone: 1800 028 365
Australian registration numbers

Adefin 10 - AUST R 92999
Adefin 20 - AUST R 93000

This leaflet was prepared on 1 December 2006.

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