Bicor 2.5mg Tablets 28


Drug Name: bisoprolol
Our Price $15.99
PBS $26.86
Concession $8.77
Safety Net $3.57

S8 Note - This prescription item is Schedule 8 and can only be supplied on a script from a registered doctor in Queensland. Any prescriptions from any other state cannot be filled and will be returned in the mail

Note: Private, PBS and our prices are available to the general public. Concession and Safety Net prices are only available to people with the appropriate concession or Safety Net cards. See Prescriptions for more details.


This prescription item requires a pre approved authority from the Government in order to get this item at the quoted price. Authority prescriptions need to be applied for by the doctor writing the script and can include reasons such as increased quantities due to dosage, increased repeats, use for a pre determined specified use, or the nature of the medication itself requiring specialist interaction. In the event that an authority is not granted on the script, the price will revert to the private price quoted for that item


This item contains more than one pack of a prescription product. Before this can be dispensed the doctor has to give approval. The prescription must be written for the total quantity or the prescription must be endorsed by your doctor "Regulation 24" otherwise we will be unable to dispense the increased amount. If you proceed with the order without approval, we will only send out one pack at the single pack price and refund the difference. Eg If your prescription is written out for 30 Tablets with 5 repeats and it does not have “Regulation 24 “ written on the script, the ONLY quantity we can dispense is 30 at one time. Further dispensing of this product could only occur after an appropriate length of time - usually 21 days but depends on dosage. In this example if you would like to obtain 180 Tablets then the doctor must endorse the prescription “Regulation 24” or the quantity must be written out for 180 and not 30. NB Conditions apply on the writing of a Regulation 24 prescription. Ask your doctor or pharmacist for details.

We can no longer accept signed authority forms from your doctor as permission to dispense more than one pack. Please contact our pharmacist for more information.

If you order this item as Private, NO PBS stickers will be issued. Once any prescription order has been sent the product cannot be returned for a refund even if your doctor changes your medication or you have an adverse reaction.

Bicor 2.5mg Tablets 28

Bicor 2.5mg Tablets 28

Product ID: 54075

Pharmacist Only Medicine

This product is a Pharmacist Only Medicine and requires pharmacist advice before we can dispatch this product. You must first place the order and then contact our pharmacists within 48 hours on 1300 367 283. The pharmacist will determine if this product is appropriate for you and if so, approve the order. In the event that you do not do this, the product will be deleted from your order and the balance of your order will be dispatched. This is not required if you have a doctor's prescription.


General Information

Consumer Medicine Information

What is in this leaflet

This leaflet answers some common questions about Bicor.

It does not contain all of the available information. It does not take the place of talking to your doctor or pharmacist.

All medicines have benefits and risks. Your doctor has weighed the risks of you taking Bicor against the benefits they expect it will have for you.

If you have any concerns about taking this medicine, talk to your doctor or pharmacist.

Keep this leaflet with your medicine. You may need to read it again.

What Bicor is used for

Bicor is used to treat heart failure. It is usually used in combination with other medicines.

Heart failure occurs when the heart muscle is weak and unable to pump enough blood to supply the body's needs. Heart failure may start off with no symptoms, but as the condition progresses patients may feel short of breath and notice swelling of the feet and ankles due to fluid build up.

Bicor belongs to a group of medicines called beta-blockers. These medicines work by affecting the body's response to some nerve impulses, especially in the heart. As a result, it decreases the heart's need for blood and oxygen and therefore reduces the amount of work the heart has to do. Bicor also slows your heart rate, which in turn increases the efficiency of your heart.

Bicor can help to reduce the number of heart failure episodes needing hospital admission and also the risk of sudden death.

Your doctor may have prescribed Bicor for another reason. Ask your doctor if you have any questions about why Bicor has been prescribed for you.

Bicor is not recommended for use in children, as the safety and efficacy in children have not been established.

Bicor is available only with a doctor's prescription.

There is no evidence that Bicor is addictive.

Before you take Bicor

When you must not take it

Do not take Bicor if you are allergic to medicines containing bisoprolol or any of the ingredients listed at the end of this leaflet. Some of the symptoms of an allergic reaction may include skin rash, itching or hives, swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing, wheezing or shortness of breath.

Do not take Bicor if you have any of the following heart problems:
severe heart failure that is not controlled medically
worsening heart failure requiring injection of medicines into a vein
cardiogenic shock, a serious heart condition causing low blood pressure and circulatory failure
certain heart conditions where the electrical activity controlling your heart rate does not work properly, causing a very slow heart rate or uneven heart beating
low blood pressure.

Do not take Bicor if you have any of the following medical conditions:
severe asthma or severe chronic obstructive lung disease
severe blood circulation problems in your limbs (such as Raynaud's syndrome), which may cause your fingers and toes to tingle or turn pale or blue
untreated phaeochromocytoma, a rare tumour of the adrenal gland
metabolic acidosis, a condition when there is too much acid in the blood.

Do not take this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering. If it has expired or is damaged, return it to your pharmacist for disposal.

Before you start to take it

Tell your doctor if you are allergic to any other medicines, foods, dyes or preservatives.

Tell your doctor if you are pregnant or plan to become pregnant. Bicor may affect your developing baby if you take it during pregnancy. Your doctor will discuss the risks and benefits of taking Bicor during pregnancy.

Tell your doctor if you are breastfeeding or wish to breastfeed. Like most beta-blocker medicines, Bicor is not recommended while you are breastfeeding. Your doctor will discuss the risks and benefits of taking Bicor when breastfeeding.

Tell your doctor if you have or have had any of the following medical conditions:
asthma, difficulty breathing or other lung problems
certain heart diseases (such as disturbances in heart rhythm or Prinzmetal angina)
any allergic conditions
psoriasis, a skin disease with thickened patches of red skin, often with silvery scales
thyroid disorder
any blood vessel disorder causing poor circulation in the arms and legs
kidney problems
liver problems
phaeochromocytoma, a rare tumour of the adrenal gland.

Your doctor may want to take special care if you have any of these conditions.

Tell your doctor if you are going to have anaesthesia (for example for surgery). Bicor may influence how your body reacts to this situation.

If you have not told your doctor about any of the above, tell them before you start taking Bicor.

Taking other medicines

Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop. Some medicines and Bicor may interfere with each other.

Do not take the following medicines with Bicor without special advice from your doctor:
certain anti-arrhythmic medicines such as disopyramide, lidocaine, phenytoin or flecainide (used to treat irregular or abnormal heartbeat)
certain calcium antagonists such as diltiazem or verapamil (used to treat high blood pressure and angina)
certain medicines used to treat high blood pressure such as clonidine, methyldopa or moxonidine.

However, do not stop taking these medicines without checking with your doctor.

Check with your doctor before taking the following medicines with Bicor.

Your doctor may need to check your condition more frequently.
anti-arrhythmic medicines such as amiodarone (used to treat irregular or abnormal heartbeat)
calcium antagonists such as felodipine or amlodipine (used to treat high blood pressure and angina)
certain medicines used to treat arthritis, pain or inflammation, such as ibuprofen or diclofenac
eye drops for glaucoma treatment
insulin and oral drugs for diabetes
anaesthetic agents used in surgery
digoxin, a medicine used to treat heart failure
ergot derivatives, medicines commonly used to treat migraines
rifampicin, a medicine used to treat tuberculosis
tricyclic antidepressants
barbiturates, medicines used to treat epilepsy
phenothiazines, medicines used to treat some mental conditions
mefloquine, a medicine used to treat malaria
adrenaline, a medicine used to treat allergic reactions
certain medicines used to treat depression called monoamine oxidase inhibitors, such as phenelzine or tranylcypromine.

These medicines may be affected by Bicor or may affect how well it works. You may need different amounts of your medicines, or you may need to take different medicines.

Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking Bicor.

How to take Bicor

How much to take

The usual starting dose is 1.25 mg once daily for a week. If well tolerated, your doctor will gradually increase your dose over the next ten weeks. The usual dose for maintenance therapy is 10 mg once daily.

If your conditions gets worse or you no longer tolerate the drug, it may be necessary to reduce the dose again or to interrupt treatment. In some patients a maintenance dose lower than 10 mg may be sufficient. Your doctor will tell you what to do.

Your doctor will monitor your blood pressure, heart rate and other vital signs carefully after you start treatment with Bicor and during dose increase.

Follow all directions given to you by your doctor and pharmacist carefully.

How to take it

Swallow the tablets with a glass of water.

Do not crush or chew the tablets. If you crush or chew Bicor tablets, they will not work as well.

When to take it

Take Bicor in the morning, with or without food.

If you forget to take it

If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to.

Otherwise, take the missed dose as soon as you remember, and then go back to taking your tablets as you would normally.

Do not take a double dose to make up for the dose you missed.

If you are not sure what to do, ask your doctor or pharmacist.

How long to take it for

To properly control your condition, Bicor must be taken every day, usually as a long term treatment.

Keep taking Bicor for as long as your doctor recommends. It is very important that you do not stop taking Bicor suddenly.

If you take too much (overdose)

Immediately telephone your doctor or the Poisons Information Centre (telephone 13 11 26) for advice, or go to Accident and Emergency at the nearest hospital, if you think you or anyone else may have taken too much Bicor. Do this even if there are no signs of discomfort or poisoning.

You may need urgent medical attention.

Symptoms of an overdose may include slowed heart rate, difficulty breathing, marked drop in blood pressure, severe heart failure, or a decrease in blood sugar.

While you are taking Bicor

Things you must do

Before starting any new medicine, tell your doctor or pharmacist that you are taking Bicor.

Tell all the doctors, dentists and pharmacists who are treating you that you are taking Bicor.

If you become pregnant while taking Bicor, tell your doctor.

If you plan to have surgery, including dental surgery, tell your doctor or dentist that you are taking Bicor.

If you are being treated for diabetes, make sure you check your blood sugar level regularly and report any changes to your doctor. Bicor may change how well your diabetes is controlled. It may also cover up some of the symptoms of low blood sugar, called hypoglycaemia, such as fast heart beat. Bicor may make hypoglycaemia last longer. Your dose of diabetic medicines, including insulin, may need to change.

If you are to have any medical tests, tell your doctor that you are taking Bicor. Bicor may affect the results of some tests.

Visit your doctor regularly so they can check on your progress. Your doctor may check your eyes, thyroid, lipid and blood glucose levels.

Tell your doctor if, for any reason, you have not taken your medicine exactly as prescribed. Your doctor may think it is not working effectively and change your treatment unnecessarily.

Things you must not do

Do not stop taking Bicor, or lower the dose, without checking with your doctor. Stopping Bicor suddenly may cause your condition to worsen or other heart complications may occur.

If you have to stop treatment, your doctor will usually advise you to reduce the dose gradually.

Do not use Bicor to treat any other conditions unless your doctor tells you to.

Do not give Bicor to anyone else, even if they have the same condition as you.

Things to be careful of

Be careful driving or operating machinery until you know how Bicor affects you. Bicor may cause tiredness, dizziness or lightheadedness in some people, especially after the first dose. If any of these occur, do not drive, operate machinery or do anything else that could be dangerous.

Be careful getting up from a sitting or lying position. Dizziness, lightheadedness or fainting may occur, especially when you get up quickly. Getting up slowly may help.

Suggestions to help manage your condition
Physical activity - regular exercise when symptoms are absent or mild helps improve heart function. Before starting any exercise, ask your doctor for advice.
Weight reduction - your doctor may suggest losing some weight to help lessen the amount of work your heart has to do.
Diet - eat a healthy low fat diet which includes plenty of fresh fruit and vegetables, bread, cereals and fish. Also, try to eat less fat and sugar.
Salt restriction - too much salt can make your heart failure worse. Try to avoid using salt in cooking and at the table.

Side effects

Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Bicor. Bicor helps most people with heart failure, but it may have unwanted side effects in some people.

All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.

Do not be alarmed by this list of possible side effects. You may not experience any of them.

Ask your doctor or pharmacist to answer any questions you may have.

Tell your doctor if you notice any of the following and they worry you:
tiredness, feeling weak
sleep disturbances, nightmares
nausea, vomiting
diarrhoea, constipation
feeling of coldness or numbness in hands or feet
allergic runny nose
hair loss
sexual problems.

Tell your doctor as soon as possible if you notice any of the following:
muscular weakness or cramps
dizziness or lightheadedness (sometimes with fainting), especially on standing up, which may be due to low blood pressure
a very slow heart beat
irritation or redness of the eye
skin reactions such as rash, flush, itching, worsening of psoriasis
difficulty hearing.

The above list includes serious side effects that may require medical attention.

Tell your doctor immediately or go to Accident and Emergency at the nearest hospital if you notice any of the following:
swelling of the face, lips, tongue throat which may cause difficulty breathing or swallowing
signs of worsening heart failure such as shortness of breath, sometimes with tiredness or weakness, swelling of the feet or legs due to fluid build up
chest tightness, wheezing, rattly breathing
yellowing of the skin or eyes, dark coloured urine, itching, generally feeling unwell
irregular heart beating.

The above list includes very serious side effects. You may need urgent medical attention or hospitalisation.

Tell your doctor if you notice anything that is making you feel unwell.

Other side effects not listed above may also occur in some patients.

After taking Bicor


Keep Bicor where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

Keep your tablets in the blister pack until it is time to take them. If you take the tablets out of the blister pack they may not keep well.

Keep your tablets in a cool dry place.

Bicor 1.25 mg (Starter Pack) and 2.5 mg should be stored below 25 degrees C.

Bicor 5 mg and 10 mg should be stored below 30 degrees C.

Do not store Bicor or any other medicine in the bathroom or near a sink.

Do not leave Bicor in the car or on window sills. Heat and dampness can destroy some medicines.


If your doctor tells you to stop taking Bicor, or your tablets have passed their expiry date, ask your pharmacist what to do with any that are left over.

Product description

What it looks like

Bicor comes in 4 strengths of tablets:
Bicor 1.25 mg (Starter Pack) - white, round film-coated tablet
Bicor 2.5 mg - white, heart-shaped, film-coated tablet with a dividing score on both sides
Bicor 5 mg - yellowish white, heart-shaped, film-coated tablet with a dividing score on both sides
Bicor 10 mg - pale orange - light orange, heart-shaped, film-coated tablet with a dividing score on both sides

Bicor 1.25 mg comes in pack of 10 tablets. The other packs contain 28 tablets.


The active ingredient in Bicor is bisoprolol fumarate.

Each Bicor 1.25 mg (Starter Pack) tablet contains 1.25 mg of bisoprolol fumarate.

The tablets also contain:
colloidal anhydrous silica
magnesium stearate
pregelatinised maize starch
maize starch
microcrystalline cellulose
anhydrous calcium hydrogen phosphate
dimethicone 100
purified talc
macrogol 400
titanium dioxide

Each Bicor 2.5 mg tablet contains 2.5 mg of bisoprolol fumarate.

The tablets also contain:
colloidal anhydrous silica
magnesium stearate
maize starch
microcrystalline cellulose
anhydrous calcium hydrogen phosphate
dimethicone 100
macrogol 400
titanium dioxide

Each Bicor 5 mg and 10 mg tablet contains 5 mg and 10 mg bisoprolol fumarate respectively.

These tablets also contain:
colloidal anhydrous silica
magnesium stearate
maize starch
microcrystalline cellulose
anhydrous calcium hydrogen phosphate
dimethicone 100
macrogol 400
titanium dioxide
iron oxide yellow (CI 77492).

Bicor 10 mg tablets also contain:
iron oxide red (CI 77491).

The tablets are gluten free.


Bicor is supplied by:
Alphapharm Pty Limited
(ABN 93 002 359 739)
Chase Building 2
Wentworth Park Road
Glebe NSW 2037
Phone: (02) 9298 3999
Medical Information
Phone: 1800 028 365
Australian registration numbers:
Bicor 1.25 mg (Starter Pack)- Aust R 81603
Bicor 2.5 mg - Aust R 81604
Bicor 5 mg - Aust R 81606
Bicor 10 mg - Aust R 81608
This leaflet was prepared on
23 September 2008.

Preferred Generic
Our preferred generic for this medication is listed below. A generic prescription medicine works in the same way as the existing medicine. What matters is the active ingredient, which is the same in the generic brands and the existing brand. Please click on it below to view the product(s).
Bisoprolol Sandoz 2.5mg Tablets 28
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Alternative Product(s)
There is generic brand to choose from in the table below. Generic Brands are less expensive brands that have been proven to have the same effect. Please select the desired brand.* *Some Doctor's will have "no substitution permitted" endorsed on the script. Please check your prescription as generics are not available in this case.
Bisoprolol Sandoz 2.5mg Tablets 28
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