Zyprexa Zydis 10mg Wafer 28


Drug Name: olanzapine
Private Price $32.50
PBS $32.16
Concession $5.20
Safety Net $0.00

S8 Note - This prescription item is Schedule 8 and can only be supplied on a script from a registered doctor in Queensland. Any prescriptions from any other state cannot be filled and will be returned in the mail

Note: Private, PBS and our prices are available to the general public. Concession and Safety Net prices are only available to people with the appropriate concession or Safety Net cards. See Prescriptions for more details.


This prescription item requires a pre approved authority from the Government in order to get this item at the quoted price. Authority prescriptions need to be applied for by the doctor writing the script and can include reasons such as increased quantities due to dosage, increased repeats, use for a pre determined specified use, or the nature of the medication itself requiring specialist interaction. In the event that an authority is not granted on the script, the price will revert to the private price quoted for that item


This item contains more than one pack of a prescription product. Before this can be dispensed the doctor has to give approval. The prescription must be written for the total quantity or the prescription must be endorsed by your doctor "Regulation 24" otherwise we will be unable to dispense the increased amount. If you proceed with the order without approval, we will only send out one pack at the single pack price and refund the difference. Eg If your prescription is written out for 30 Tablets with 5 repeats and it does not have “Regulation 24 “ written on the script, the ONLY quantity we can dispense is 30 at one time. Further dispensing of this product could only occur after an appropriate length of time - usually 21 days but depends on dosage. In this example if you would like to obtain 180 Tablets then the doctor must endorse the prescription “Regulation 24” or the quantity must be written out for 180 and not 30. NB Conditions apply on the writing of a Regulation 24 prescription. Ask your doctor or pharmacist for details.

We can no longer accept signed authority forms from your doctor as permission to dispense more than one pack. Please contact our pharmacist for more information.

If you order this item as Private, NO PBS stickers will be issued. Once any prescription order has been sent the product cannot be returned for a refund even if your doctor changes your medication or you have an adverse reaction.

Zyprexa Zydis 10mg Wafer 28

Zyprexa Zydis 10mg Wafer 28

Product ID: 54056

Pharmacist Only Medicine

This product is a Pharmacist Only Medicine and requires pharmacist advice before we can dispatch this product. You must first place the order and then contact our pharmacists within 48 hours on 1300 367 283. The pharmacist will determine if this product is appropriate for you and if so, approve the order. In the event that you do not do this, the product will be deleted from your order and the balance of your order will be dispatched. This is not required if you have a doctor's prescription.


General Information

Consumer Medicine Information

What is in this leaflet

This leaflet is designed to provide you with answers to some common questions about this medicine. It does not contain all the available information and does not take the place of talking with your doctor.

All medicines have risks and benefits.

Your doctor has more information about this medicine than is contained in this leaflet. Also, your doctor has had the benefit of taking a full and detailed history from you and is in the best position to make an expert judgement to meet your individual needs.

If you have any concerns about taking this medicine, talk to your doctor or pharmacist.

Keep this leaflet with this medicine. You may need to read it again.

What ZYPREXA is used for

ZYPREXA is used to treat symptoms of schizophrenia and related psychoses. ZYPREXA alone, or in combination with lithium or valproate, is used for the short-term treatment of acute manic episodes associated with Bipolar I Disorder. ZYPREXA is also a mood stabiliser that prevents further occurrences of the disabling high and low (depressed) extremes of mood associated with Bipolar I Disorder.

Schizophrenia is a mental illness with disturbances in thinking, feelings and behaviour. Bipolar I Disorder is a mental illness with symptoms such as feeling "high", having excessive amounts of energy, needing much less sleep than usual, talking very quickly with racing ideas and sometimes severe irritability.

ZYPREXA IM injection is used for the rapid control of agitation and disturbed behaviours in patients with schizophrenia and related psychoses and in patients with acute mania associated with Bipolar I Disorder.

ZYPREXA IM injection is given when treatment with ZYPREXA tablets is not appropriate. Your doctor will change your treatment to ZYPREXA tablets, as soon as practicable.

ZYPREXA belongs to a group of medicines called antipsychotics. It helps to correct chemical imbalances in the brain, which may cause mental illness.

Your doctor may have prescribed ZYPREXA for another reason. Ask your doctor if you have any questions about why ZYPREXA has been prescribed for you.

This medicine is available only with a doctor's prescription.

Before taking ZYPREXA

Tell your doctor if you have any of the following conditions or if you have ever experienced any of these conditions.

When you must not take it

Do not take ZYPREXA:
if you have had an allergic reaction to ZYPREXA or to any of the ingredients listed at the end of this leaflet (see 'Product Description'). Signs of an allergic reaction may include a skin rash, itching, shortness of breath or swelling of the face, lips or tongue.
if the packaging is torn or shows signs of tampering or the tablets or wafers do not look quite right.
if the expiry date on the pack has passed. If you take this medicine after the expiry date has passed it may not work as well.

If you are not sure whether you should start taking ZYPREXA, talk to your doctor or pharmacist.

Before you start to take it

You must tell your doctor:
if you have had an allergic reaction to any medicine which you have taken previously to treat your current condition.
if you have or have had any medical conditions, especially the following:

- tumour of the pituitary gland (a small gland at the base of the brain)
- disease of the blood with a reduced number of white or red blood cells
- disease of the blood vessels of the brain, including stroke
- prostate problems
- kidney or liver disease
- high blood sugar, diabetes or a family history of diabetes
- breast cancer or a family history of breast cancer
- paralytic ileus, a condition where the small bowel does not work properly
- epilepsy, seizures or fits
- glaucoma, a condition in which there is usually a build up of fluid in the eye
- heart disease
- neuroleptic malignant syndrome, a reaction to some medicines with a sudden increase in body temperature, extremely high blood pressure and severe convulsions
- tardive dyskinesia, a reaction to some medicines with uncontrollable twitching or jerking movements of the arms and legs.
if you are pregnant or intend to become pregnant.

Like most antipsychotic medicines, ZYPREXA is not recommended for use during pregnancy. If there is a need to consider ZYPREXA during your pregnancy, your doctor will discuss with you the benefits and risks of using it.
if you are breast-feeding or plan to breast-feed.

It is recommended that you do not breast-feed while taking ZYPREXA.
if you suffer from lactose intolerance (because ZYPREXA tablets contain lactose).
if you suffer from phenylketonuria (because ZYPREXA Zydis wafers contain aspartame).

ZYPREXA is not recommended for use in children under the age of 18 years.

Taking other medicines

Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from your pharmacy, supermarket or health food shop. Some medicines may be affected by ZYPREXA or may affect how it works. These include:
medicines used to treat a fast or irregular heart beat (arrhythmia)
medicines taken for anxiety or to help you sleep
medicines taken for depression
carbamazepine, a medicine used for mood stabilisation and to treat epilepsy
other centrally acting medicines (eg. tranquillisers)
ciprofloxacin, a medicine used to treat bacterial infections
medicines that lower blood pressure
medicines used for Parkinson's disease.

Smoking may affect ZYPREXA or may affect how it works.

Your doctor or pharmacist has more information on medicines to be careful with or avoid while taking ZYPREXA.

Tell your doctor about these things before you take ZYPREXA.

How to take ZYPREXA

Follow all directions given to you by your doctor or pharmacist carefully. These may differ from the information contained in this leaflet.

How much to take

ZYPREXA tablets or wafers:

Your doctor will tell you how many ZYPREXA tablets or wafers you should take. The dose your doctor will prescribe for you will usually be in the range 5 mg to 20 mg per day.

Your doctor may increase or decrease your dose in order to find the appropriate dose for your condition.

A lower starting dose may be prescribed for elderly patients over the age of 65 years.

ZYPREXA IM Injection:

Your doctor will decide how much ZYPREXA you need and how long you need it for.

The dosage you receive will usually be 10 mg in one injection. Up to three injections in 24 hours may be given.

A lower starting dose may be prescribed for elderly patients over the age of 65 years.

How to take it

ZYPREXA tablets:

ZYPREXA tablets should be swallowed whole with a glass of water.

ZYPREXA Zydis wafers:

ZYPREXA Zydis wafers break easily, so you should handle them carefully.

Do not handle the wafers with wet hands as the wafers may break up.
1. Hold the blister strip at the edges and separate one blister cell from the rest of the strip by gently tearing along the perforations around it.
2. Carefully peel off the purple coloured backing.
3. Gently push the wafer out.
4. Put the wafer in your mouth. It will dissolve directly in your mouth, so that it can be easily swallowed.

You can also place the wafer in a full glass or cup of water, orange juice, apple juice, milk or coffee, and stir. Drink it straight away. With some drinks, the mixture may change colour and possibly become cloudy.

The wafer should not be placed in cola drinks.

ZYPREXA IM Injection:

ZYPREXA is injected into your muscle. Your doctor or nurse will inject ZYPREXA for you.

When to take it

ZYPREXA tablets or wafers should be taken once a day as advised by your doctor. Take your prescribed dose at the same time each day. ZYPREXA tablets or wafers can be taken with or without food.

How long do I take it

Do not stop taking ZYPREXA just because you feel better. It is important that you do NOT stop taking ZYPREXA unless your doctor tells you.

If you forget to take it

If it is almost time for your next dose skip the dose you missed and take your next dose when you are meant to. Otherwise, take it as soon as you remember then go back to taking your medicine as you would normally.

Do not take a double dose to make up for the dose that you missed.

If you are not sure what to do, ask your doctor or pharmacist.

If you take too much

Immediately telephone your doctor or the Australian Poisons Information Centre (telephone 13 11 26) or the New Zealand National Poisons Centre (0800 POISON or 0800 764 766), or go to Accident and Emergency at your nearest hospital, if you think that you or anyone else has taken too much ZYPREXA. Do this even if there are no signs of discomfort or poisoning. If you have taken too much ZYPREXA, the most common signs are fast heart beat, agitation/aggression, difficulty speaking, uncontrollable movements and sedation.

While you are taking ZYPREXA

Things you must do

It is important that you remember to take ZYPREXA daily and at the dose prescribed by your doctor.

Tell all doctors, dentists and pharmacists who are treating you that you are taking ZYPREXA.

While you are taking ZYPREXA, tell your doctor or pharmacist before you start any new medicine.

If you become pregnant while taking ZYPREXA, tell your doctor.

Keep all of your doctor's appointments so that your progress can be checked. Your doctor should monitor your weight while you are taking ZYPREXA.

Patients with diabetes or who have a higher chance of developing diabetes should have their blood sugar checked often.

If you are over 65, your doctor may measure your blood pressure from time to time.

Things you must not do

Do not stop taking ZYPREXA, or lower the dosage, even if you are feeling better, without checking with your doctor.

Do not give ZYPREXA to anyone else, even if their symptoms seem similar or they have the same condition as you. Your doctor has prescribed ZYPREXA for you and your condition.

Things to be careful of

ZYPREXA may cause drowsiness in some people. Be careful driving or operating machinery until you know how ZYPREXA affects you.

Be careful when drinking alcohol while taking ZYPREXA. The effects of alcohol could be made worse while taking ZYPREXA. Your doctor may suggest you avoid alcohol while you are being treated with ZYPREXA.

If ZYPREXA makes you feel light-headed, dizzy or faint, be careful when getting up from a sitting or lying position. Getting up slowly may help.

If outdoors, wear protective clothing and use at least a 15+ sunscreen. ZYPREXA may cause your skin to be much more sensitive to sunlight than it is normally.

Exposure to sunlight may cause a skin rash, itching, redness, or severe sunburn. If your skin does appear to be burning, tell your doctor.

Make sure you keep cool in hot weather and keep warm in cool weather. ZYPREXA may affect the way your body reacts to temperature changes

Side effects

Tell your doctor or pharmacist as soon as possible if you experience any undesirable effect or feel unwell while you are taking ZYPREXA. Like other medicines, ZYPREXA may cause some unwanted side effects. These are likely to vary from patient to patient. Some side effects may be related to the dose of ZYPREXA. Accordingly, it is important that you tell your doctor as soon as possible about any unwanted effects. Your doctor may then decide to adjust the dose of ZYPREXA you are taking.

Tell your doctor if you notice any of the following side effects and they worry you:
restlessness or difficulty sitting still
weight gain
increased appetite
dry mouth
swelling of your hands, feet and ankles
unusual tiredness or weakness.

Some people may feel dizzy in the early stages of treatment, especially when getting up from a lying or sitting position. This side effect usually passes after taking ZYPREXA for a few days.

Elderly patients with dementia-related psychosis may notice the following side effects:
unusual manner of walking
inability to retain urine (urinary incontinence).

Some patients with Parkinson's disease may hallucinate (see, feel or hear things that are not there) or develop worsening symptoms of Parkinson's disease.

Patients with bipolar mania taking ZYPREXA in combination with lithium or valproate may notice the following additional side effects:
speech disorder.

Tell your doctor if you notice any of the above side effects and they worry you. These are the more common side effects of ZYPREXA.

Additional side effects seen with ZYPREXA IM Injection are:
low blood pressure
slow heart beat
fast heart beat.

Tell your doctor if you notice any of the following side effects:
symptoms of sunburn (such as redness, itching, swelling or blistering of the skin) which occur more quickly than normal
allergic reaction
slow heart beat
prolonged and/or painful erection
unusual secretion of breast milk
breast enlargement
symptoms of high sugar levels in the blood (including passing large amounts of urine, excessive thirst, having a dry mouth and skin and weakness). These may indicate the onset or worsening of diabetes
reaction following abrupt discontinuation (profuse sweating, nausea or vomiting)
absence of menstrual periods and changes in the regularity of menstrual periods
difficulty in initiating urination
unusual hair loss or thinning.

Tell your doctor if your monthly periods are absent for six months or more.

These side effects are uncommon but may require medical attention.

Tell your doctor immediately or go to Accident and Emergency at your nearest hospital if you notice any of the following:
frequent infections such as fever, severe chills, sore throat or mouth ulcers
bleeding or bruising more easily than normal
seizures, fits or convulsions
yellowing of the skin and/or eyes
nausea, vomiting, loss of appetite, generally feeling unwell, fever, itching, yellowing of the skin and/or eyes
inflammation of the pancreas
severe upper stomach pain often with nausea and vomiting
worm-like movements of the tongue, or other uncontrolled movements of the tongue, mouth, cheeks, or jaw which may progress to the arms and legs
sudden increase in body temperature, sweating, fast heart beat, muscle stiffness, high blood pressure and convulsions
sharp chest pain, coughing of blood, or sudden shortness of breath
pain/tenderness in the calf muscle area
muscle pain, muscle weakness and brown urine.

These are very serious side effects. You may need urgent medical attention or hospitalisation. All of these side effects are very rare.

Also, some side effects, such as changes to liver function, cholesterol or tricylcerides can occur. These can only be found when your doctor does tests from time to time to check your progress.

Do not be alarmed by this list of side effects. You may not experience any of them.

Other side effects not listed above may also occur in some patients. Tell your doctor if you notice anything else that is making you feel unwell.

Tell your doctor if you notice anything unusual or if you are concerned about any aspect of your health, even if you think the problems are not connected with this medicine and are not referred to in this leaflet.

After taking ZYPREXA


Keep your tablets and wafers in the blister pack until it is time to take them.

Keep your tablets and wafers in a cool, dry place where the temperature stays below 25°C.

ZYPREXA Zydis wafers should be kept out of direct light.

ZYPREXA IM Injection vials should be stored below 25°C. The vials are usually stored in the hospital ward or in the pharmacy.

All medicines should be kept where young children cannot reach them.

There will be an expiry date (month, year) on your ZYPREXA container.

The medicine should not be taken after this date because it may have lost some of its strength.


If your doctor tells you to stop taking ZYPREXA or you find that the tablets or wafers have passed their expiry date, please return any left over tablets or wafers to your pharmacist.

Product Description

What it looks like

ZYPREXA tablets are white and are available in the following strengths:
2.5 mg tablet
5 mg tablet
7.5 mg tablet (Australia only)
10 mg tablet.

Each ZYPREXA tablet has "Lilly" and an identicode number printed on it. The identicode number for:
2.5 mg tablet is 4112
5 mg tablet is 4115
7.5 mg tablet is 4116
10 mg tablet is 4117.

ZYPREXA Zydis wafers are yellow and are available in the following strengths:
5 mg wafer
10 mg wafer.

ZYPREXA IM Injection comes as a yellow powder in a clear glass vial. A vial of ZYPREXA IM Injection can provide you with 10 mg of olanzapine.


ZYPREXA tablets:

Active Ingredient:
2.5 mg tablet - 2.5 mg olanzapine per tablet
5 mg tablet - 5 mg olanzapine per tablet
7.5 mg tablet - 7.5 mg olanzapine per tablet
10 mg tablet - 10 mg olanzapine per tablet.

Inactive Ingredients - lactose, hydroxypropylcellulose, crospovidone, microcrystalline cellulose, magnesium stearate, hypromellose and carnauba wax, Colour Mixture White YS-1-18027-A and Edible Blue Ink.

ZYPREXA Zydis wafers:

Active Ingredient:
5 mg wafer - 5 mg olanzapine per wafer
10 mg wafer - 10 mg olanzapine per wafer.

Inactive ingredients - gelatin, mannitol, aspartame, sodium methyl hydroxybenzoate and sodium propyl hydroxybenzoate.

ZYPREXA IM Injection:

Active Ingredient - 10 mg olanzapine.

Inactive Ingredients - lactose, tartaric acid.


ZYPREXA is a product of:

Eli Lilly Australia Pty Limited
112 Wharf Road

ZYPREXA is distributed in New Zealand by:

Eli Lilly and Company (NZ) Ltd.
Level 3, Axon House
414-422 Khyber Pass Road
Newmarket, Auckland

® = Registered Trademark

Australian Registration Numbers

ZYPREXA tablets:

2.5 mg tablet - AUST R 56603
5 mg tablet - AUST R 56604
7.5 mg tablet - AUST R 56605
10 mg tablet - AUST R 56606
ZYPREXA Zydis wafers:
5 mg wafer - AUST R 73388
10 mg wafer - AUST R 73389
AUST R 76867
This leaflet was revised in April 2008.

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