Largactil 100mg Tablets 100


Drug Name: chlorpromazine
Our Price $13.99
PBS $20.67
Concession $5.20
Safety Net $0.00

S8 Note - This prescription item is Schedule 8 and can only be supplied on a script from a registered doctor in Queensland. Any prescriptions from any other state cannot be filled and will be returned in the mail

Note: Private, PBS and our prices are available to the general public. Concession and Safety Net prices are only available to people with the appropriate concession or Safety Net cards. See Prescriptions for more details.


This prescription item requires a pre approved authority from the Government in order to get this item at the quoted price. Authority prescriptions need to be applied for by the doctor writing the script and can include reasons such as increased quantities due to dosage, increased repeats, use for a pre determined specified use, or the nature of the medication itself requiring specialist interaction. In the event that an authority is not granted on the script, the price will revert to the private price quoted for that item


This item contains more than one pack of a prescription product. Before this can be dispensed the doctor has to give approval. The prescription must be written for the total quantity or the prescription must be endorsed by your doctor "Regulation 24" otherwise we will be unable to dispense the increased amount. If you proceed with the order without approval, we will only send out one pack at the single pack price and refund the difference. Eg If your prescription is written out for 30 Tablets with 5 repeats and it does not have “Regulation 24 “ written on the script, the ONLY quantity we can dispense is 30 at one time. Further dispensing of this product could only occur after an appropriate length of time - usually 21 days but depends on dosage. In this example if you would like to obtain 180 Tablets then the doctor must endorse the prescription “Regulation 24” or the quantity must be written out for 180 and not 30. NB Conditions apply on the writing of a Regulation 24 prescription. Ask your doctor or pharmacist for details.

We can no longer accept signed authority forms from your doctor as permission to dispense more than one pack. Please contact our pharmacist for more information.

If you order this item as Private, NO PBS stickers will be issued. Once any prescription order has been sent the product cannot be returned for a refund even if your doctor changes your medication or you have an adverse reaction.

Largactil 100mg Tablets 100

Largactil 100mg Tablets 100

Product ID: 53781

Pharmacist Only Medicine

This product is a Pharmacist Only Medicine and requires pharmacist advice before we can dispatch this product. You must first place the order and then contact our pharmacists within 48 hours on 1300 367 283. The pharmacist will determine if this product is appropriate for you and if so, approve the order. In the event that you do not do this, the product will be deleted from your order and the balance of your order will be dispatched. This is not required if you have a doctor's prescription.


General Information

Consumer Medicine Information

What is in this leaflet

This leaflet answers some common questions about Largactil.

It does not contain all the available information.

It does not take the place of talking to your doctor or pharmacist.

All medicines have risks and benefits. Your doctor or pharmacist has weighed the risks of you taking Largactil against the benefits they expect it will have for you.

If you have any concerns about taking this medicine, ask your doctor or pharmacist.

Keep this leaflet with this medicine. You may need to read it again.

What Largactil is used for

The active ingredient of Largactil is chlorpromazine hydrochloride, one of a group of medicines called phenothiazines.

Largactil is used to treat a number of conditions and may be used either for a short time or for a long time. Largactil is used to treat various problems such as severe depression or behavioural disturbances. Largactil can also be used to treat nausea, vomiting, severe pain and unstoppable hiccups. Your doctor may have prescribed Largactil for another reason.

Ask your doctor if you have any questions about why Largactil has been prescribed for you.

Largactil is available only with a doctor's prescription.

Before you use Largactil

When you must not take it

Do not take Largactil if you have an allergy or any other reaction to Largactil or any of the ingredients listed at the end of this leaflet.

Do not take Largactil if you have any of the following:
Circulatory, blood or bone marrow problems
High blood pressure
Liver problems

Do not take Largactil after the expiry date (EXP) printed on the pack. If you take this medicine after the expiry date has passed, it may not work as well.

Do not take Largactil if the packaging is torn or shows signs of tampering or if the tablet, syrup or ampoule doesn't look quite right.

If you are not sure whether you should start taking Largactil, contact your doctor or pharmacist.

Before you start to take it

Tell your doctor or pharmacist if you have allergies to:
Any other medicines
Any other substances, such as foods, preservatives or dyes

Tell your doctor or pharmacist if you are pregnant or intend to become pregnant. Your doctor or pharmacist will discuss the possible risks and benefits of using Largactil during pregnancy.

Tell your doctor or pharmacist if you are breast-feeding or plan to breast-feed. Your doctor or pharmacist will discuss the possible risks and benefits of using Largactil during breastfeeding.

Tell your doctor or pharmacist if you have or have had any medical conditions, especially the following:
Kidney or liver disease
Decreased thyroid activity (hypoparathyroidism)
Parkinson's disease
Prostate problems
Epilepsy - fits and seizures
Glaucoma - high pressure in the eye
Muscle weakness (Myasthenia Gravis)
Chronic respiratory disorders

If you have not told your doctor or pharmacist about any of the above, tell them before you start taking Largactil.

Taking other medicines

Tell your doctor or pharmacist if you are taking any other medicines, including any that you buy without a prescription from your pharmacy, supermarket or health food shop. Some medicines and Largactil may interfere with each other. These include:
Benztropine - a drug used to treat Parkinson's Disease
Antacid - used to treat stomach upsets
Lithium - used to treat mood disorders
Barbiturates - a group of drugs used as sedatives
Tricyclic anti depressants
Benzodiazepines - a group of drugs used to treat anxiety and muscle spasms
Opioids - a group of pain killing drugs
Antidiabetic agents
Levodopa - a drug used to treat Parkinson's disease
Valproic acid - a drug used to treat epilepsy
Thiazides - diuretics (fluid tablets)
MAOI - a group of drugs used to treat depression
Prochlorperazine - a drug used to treat nausea and vomiting
Desferrioxamine - a drug used to treat iron poisoning

These medicines may be affected by Largactil, or they may affect how well it works. You may need different amounts of your medicine, or you may need to use different medicines. Your doctor or pharmacist will advise you.

Your doctor and pharmacist may have more information on medicines to be careful with or to avoid while taking Largactil.

How to take Largactil

How much to take

Your doctor or pharmacist will tell you how many tablets or how much syrup you will need to take each day. This depends on your condition and whether or not you are taking any other medicines.

Follow all directions given to you by your doctor and pharmacist carefully.

If you do not understand the instructions on the pack, ask your doctor or pharmacist for help.

How to take it

Swallow the prescribed dose of Largactil tablets whole with a full glass of water. Do not chew the tablets.

Swallow the prescribed dose of Largactil syrup and follow with a glass of water.

Largactil may be given as an injection into a muscle or as a slow injection into a vein. Largactil injections should only be given by a doctor, nurse or other trained person.

When to take it

Take Largactil at about the same time each day. Taking your tablets or syrup at the same time each day will have the best effect. It will also help you remember when to take the tablets or syrup.

If you forget to take it

If you miss a dose, simply continue to take Largactil as advised by your doctor or pharmacist. You do not need to make up for the missed dose.

Do not take a double dose to make up for the dose that you missed. This may increase the chance of you getting an unwanted side effect.

If you are not sure what to do, ask your doctor or pharmacist. If you have trouble remembering to take your medicine, ask your pharmacist for some hints.

How long to take it

Continue taking Largactil until your doctor or pharmacist tells you to stop. Do not stop using it unless your doctor or pharmacist tells you to, even if you feel better.

If you take too much (overdose)

Immediately telephone your doctor or pharmacist or the Poisons Information Centre (telephone Australia 13 11 26, New Zealand 0800 POISON or 0800 764766), or go to accident and emergency at your nearest hospital, if you think that you or anyone else may have taken too much Largactil. Do this even if there are no signs of discomfort or poisoning.

You may need urgent medical attention. If you take too much Largactil, you may experience:
Breathing difficulties
Fast heart rate
Muscle twitching

While you are using Largactil

Things you must do

Tell any other doctors, dentists, and pharmacists who are treating you that you are taking Largactil.

If you plan to have surgery that needs a general anaesthetic, tell your doctor or dentist that you are taking Largactil.

If you become pregnant while taking Largactil, tell your doctor or pharmacist.

You should avoid very cold or very hot environments. Largactil may make it difficult for your body to regulate its temperature.

You should avoid exposure to strong sunlight while you are taking Largactil. If exposure to strong sunlight is unavoidable, suitable clothing, including a hat, should be worn. A sunscreen with a high level of protection should also be used.

Things you must not do

Do not give Largactil to anyone else, even if they have the same condition as you.

Do not take Largactil to treat any other complaints unless your doctor or pharmacist tells you to.

Things to be careful of

Be careful driving or operating machinery until you know how Largactil affects you. Largactil may cause drowsiness in some people. Make sure you know how you react to Largactil before you drive a car, operate machinery, or do anything else that could be dangerous if you are dizzy or light-headed. If this occurs, do not drive. If you drink alcohol, dizziness or light-headedness may be worse.

Side effects

Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Largactil. Largactil helps most people, but it may have unwanted side effects in a few people. All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.

If you are over 65 years of age, you may have an increased chance of getting side effects.

Ask your doctor or pharmacist to answer any questions you may have.

Tell your doctor or pharmacist if you notice any of the following and they worry you:
Dizziness or light headedness
Skin problems or discolouration
Drowsiness or tiredness
Dry mouth
Difficulty in urinating
Blurred vision

These are the more common side effects of Largactil. Mostly these are mild and short-lived.

If any of the following happen, stop taking Largactil and tell your doctor or pharmacist immediately or go to casualty at your nearest hospital:
Sore throat, fever or any sign of infection
Breathing difficulty
Seizures or fits
Unwanted muscle movements of the mouth, tongue, jaw, cheeks or arms and legs.
Hardness or rigidity of the muscles.
Fast heartbeat

These are very serious side effects. You may need urgent medical attention or hospitalisation.

Other side effects not listed above may occur in some patients. Tell your doctor or pharmacist if you notice anything that is making you feel unwell.

Do not be alarmed by this list of possible side effects. You may not experience any of them.


Largactil ampoules for injection will be stored in the pharmacy or on the ward. The injection is kept in a cool dry place, protected from light.

Keep your tablets in the pack until it is time to take them. If you take the tablets out of the pack they will not keep as well.

Keep your tablets or syrup in a cool dry place. Do not store Largactil or any other medicine in the bathroom or near a sink. Do not leave it in the car on hot days or on window sills. Heat and dampness can destroy some medicines.

Keep it where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.


If your doctor or pharmacist tells you to stop taking Largactil or the tablets or syrup has passed the expiry date, ask your pharmacist what to do with any that are left over.

Product description

What it looks like

Largactil tablets are white film coated tablets with embossing on one side:

10mg tablet: LG / 10 25mg tablet: LG / 25 100mg tablet: LG / 100 Tablets are available in blister packs of 100. Largactil syrup is a dark orange syrupy liquid with the odour of spearmint / peppermint, and is slightly fruity. Syrup is available in an amber glass 100mL bottle with a childproof cap. Largactil for injection is a clear liquid in a 2mL glass ampoule, in a pack of 10 ampoules. Ingredients

Largactil tablets contain:
Chlorpromazine hydrochloride 10mg, 25mg, or 100mg (active ingredient)
Lactose monohydrate
Maize starch
Colloidal silicon dioxide
Magnesium stearate
Polyethylene glycol
Titanium dioxide
Largactil syrup contains:
Chlorpromazine hydrochloride 25mg/5mL (active ingredient)
Citric acid anhydrous
Polysorbate 20
Peppermint oil
Spearmint oil
Sodium citrate
Ascorbic acid
Sodium sulphite anhydrous
Sodium metabisulphite
Sodium benzoate
Fruit cup essence
Demineralised water
Largactil ampoules contain:
Chlorpromazine hydrochloride 50mg/2mL (active ingredient)
Sodium sulfite anhydrous
Sodium metabisulphite
Sodium chloride
Sodium citrate
Water for injections
Aventis Pharma Pty. Ltd.
12-24 Talavera Road
Macquarie Park NSW 2113
Aventis Pharma Limited
Auckland, New Zealand
Largactil® is a registered trademark.
Australian Registration Numbers:

10mg tablet AUST R 51620
25mg tablet AUST R 51618
100mg tablet AUST R 51619
25mg/5mL syrup AUST R 118128
50mg/2mL ampoule AUST R 27511
This leaflet was prepared in February 2006
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