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Diabex 1000mg Tablets 90

IMPORTANT NOTE – A VALID AUSTRALIAN PRESCRIPTION IS REQUIRED BEFORE THIS ITEM CAN BE SHIPPED

Drug Name: metformin
Our Price $11.99
PBS $20.64
Concession $9.04
Safety Net $3.84

S8 Note - This prescription item is Schedule 8 and can only be supplied on a script from a registered doctor in Queensland. Any prescriptions from any other state cannot be filled and will be returned in the mail

Note: Private, PBS and our prices are available to the general public. Concession and Safety Net prices are only available to people with the appropriate concession or Safety Net cards. See Prescriptions for more details.

GOVERNMENT AUTHORITY SCRIPT

This prescription item requires a pre approved authority from the Government in order to get this item at the quoted price. Authority prescriptions need to be applied for by the doctor writing the script and can include reasons such as increased quantities due to dosage, increased repeats, use for a pre determined specified use, or the nature of the medication itself requiring specialist interaction. In the event that an authority is not granted on the script, the price will revert to the private price quoted for that item

WARNING - MULTIPLE PACK PRESCRIPTION - PLEASE READ CAREFULLY

This item contains more than one pack of a prescription product. Before this can be dispensed the doctor has to give approval. The prescription must be written for the total quantity or the prescription must be endorsed by your doctor "Regulation 24" otherwise we will be unable to dispense the increased amount. If you proceed with the order without approval, we will only send out one pack at the single pack price and refund the difference. Eg If your prescription is written out for 30 Tablets with 5 repeats and it does not have “Regulation 24 “ written on the script, the ONLY quantity we can dispense is 30 at one time. Further dispensing of this product could only occur after an appropriate length of time - usually 21 days but depends on dosage. In this example if you would like to obtain 180 Tablets then the doctor must endorse the prescription “Regulation 24” or the quantity must be written out for 180 and not 30. NB Conditions apply on the writing of a Regulation 24 prescription. Ask your doctor or pharmacist for details.

We can no longer accept signed authority forms from your doctor as permission to dispense more than one pack. Please contact our pharmacist for more information.

If you order this item as Private, NO PBS stickers will be issued. Once any prescription order has been sent the product cannot be returned for a refund even if your doctor changes your medication or you have an adverse reaction.

Diabex 1000mg Tablets 90

Diabex 1000mg Tablets 90

Product ID: 47317
$11.99

Pharmacist Only Medicine

This product is a Pharmacist Only Medicine and requires pharmacist advice before we can dispatch this product. You must first place the order and then contact our pharmacists within 48 hours on 1300 367 283. The pharmacist will determine if this product is appropriate for you and if so, approve the order. In the event that you do not do this, the product will be deleted from your order and the balance of your order will be dispatched. This is not required if you have a doctor's prescription.

 

General Information

Consumer Medicine Information

What is in this leaflet

This leaflet answers some common questions about Diabex.

It does not contain all the available information. It does not take the place of talking to your doctor, pharmacist or diabetes educator.

All medicines have benefits and risks. Your doctor has weighed the risks of you taking Diabex against the benefits expected for you.

If you have any concerns about taking this medicine, talk to your doctor, pharmacist or diabetes educator.

Keep this leaflet with your medicine. You may need to read it again.

What Diabex is used for

Diabex is used to control blood glucose (the amount of sugar in the blood) in people with diabetes mellitus.

Diabex can be used in type 2 diabetes in adults and children over 10 years of age. It is especially useful in those who are overweight, when diet and exercise are not enough to lower high blood glucose levels (hyperglycaemia). For adult patients, metformin can be used alone, or in combination with other oral diabetic medicines or in combination with insulin in insulin requiring type 2 diabetes.

Ask your doctor if you have any questions about why Diabex has been prescribed for you. Your doctor may have prescribed Diabex for another reason.

Diabex is available only with a doctor's prescription.

There is no evidence that Diabex is addictive.

How Diabex works

Diabex belongs to a group of medicines called biguanides. Diabex lowers high blood glucose (hyperglycaemia) by helping your body make better use of the insulin produced by your pancreas.

People with type 2 diabetes are unable to make enough insulin or their body does not respond properly to the insulin it does make. This causes a build up of glucose in the blood, which can lead to serious medical problems.

Long-term hyperglycaemia can lead to heart disease, blindness, kidney damage, poor blood circulation and gangrene.

Signs of hyperglycaemia may include:
tiredness or lack of energy
headache
thirst
passing large amounts of urine
blurred vision.

Before you take Diabex

When you must not take it

Do not take Diabex if you are allergic to:
medicines containing metformin (e.g. Diaformin, Glucophage) or any other biguanide
any of the ingredients listed at the end of this leaflet.

Some of the symptoms of an allergic reaction may include skin rash, itching or hives; swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing; wheezing or shortness of breath.

Do not take Diabex if you have any of the following conditions:
type 1 diabetes mellitus that is well controlled by insulin alone
type 2 diabetes that is already well controlled by diet alone
diabetic ketoacidosis (a symptom of uncontrolled diabetes, in which substances called ketone bodies build up in the blood - you may notice this as an unusual fruity odour on your breath, difficulty breathing, confusion and frequent urination)
severe liver disease
excessive alcohol intake, binge drinking, alcohol dependence
kidney failure or severe kidney disease
dehydration, severe blood loss, shock
a severe infection
certain heart or blood vessel problems, including a recent heart attack or severe heart failure (when the heart fails to pump blood effectively)
severe breathing difficulties
blood clots in the lungs (symptoms include coughing, shortness of breath, chest pain and a fast heart rate)
gangrene
inflammation of the pancreas (pancreatitis), symptoms include severe upper stomach pain, often with nausea and vomiting.

Do not take Diabex if you plan to have any X-ray procedures requiring an injection of iodinated contrast (dye). Using this type of dye while you are taking Diabex may cause severe kidney problems and increase the risk of a serious condition called lactic acidosis. Your doctor will tell you when to temporarily stop taking the tablets before the X-ray and when it is safe to restart them.

Do not take Diabex if you are pregnant or plan to become pregnant. The safety of Diabex in pregnant women has not been established.

Insulin is more suitable for controlling blood glucose during pregnancy. Your doctor will replace Diabex with insulin while you are pregnant.

Do not take Diabex if you are breastfeeding. Diabex is not recommended while you are breastfeeding. Your doctor will discuss the options available to you.

Do not take Diabex if the expiry date (EXP) printed on the pack has passed. If you take this medicine after the expiry date it may not work as well.

Do not take Diabex if the packaging shows signs of tampering or the tablets do not look quite right.

If you are not sure whether you should start taking Diabex, ask your doctor.

Before you start to take it

Tell your doctor if you are allergic to any other medicines, foods, dyes or preservatives.

Tell your doctor if you have any medical conditions, especially the following:
heart failure
kidney problems.

Your doctor may want to take special care if you have any of these conditions.

Tell your doctor if you drink alcohol. Alcohol can affect the control of your diabetes. Drinking excessive amounts of alcohol while you are being treated with Diabex may also lead to serious side effects. Your doctor may suggest you stop drinking or reduce the amount of alcohol you drink.

If you have not told your doctor about any of the above, tell him/her before you start taking Diabex.

Taking other medicines

Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop.

Some medicines may be affected by Diabex or may affect how well it works. These include:
sulfonylureas, a group of medicines used to treat diabetes, such as gliclazide (e.g. Diamicron, Glyade), glipizide (Minidiab, Melizide), glimepiride (Amaryl, Dimirel).
repaglinide (Novonorm), another type of medicine used to treat diabetes.
some medicines used to treat high blood pressure and some heart conditions, including beta-blockers, calcium channel blockers and ACE inhibitors; some examples include metoprolol (e.g. Betaloc, Minax), nifedipine (e.g. Adalat, Adefin) and enalapril (e.g. Renitec, Alphapril).
medicines used to prevent blood clots such as warfarin (Coumadin, Marevan).
diuretics, also called fluid tablets (e.g. Lasix).,
thyroid preparations such as thyroxine (e.g. Oroxine).
cimetidine (e.g. Magicul, Tagamet), a medicine commonly used to treat reflux and ulcers.
glucocorticoids such as prednisone (Panafcort, Sone), cortisone (Cortate)
beta-2-antagonists.

Your doctor or pharmacist can tell you what to do if you are taking any of these medicines. They also have more information on medicines to be careful with or avoid while taking Diabex.

If you are not sure whether you are taking any of these medicines, check with your doctor or pharmacist.

How to take Diabex

Follow all directions given to you by your doctor and pharmacist carefully. They may differ from the information contained in this leaflet.

If you do not understand the instructions on the pack, ask your doctor or pharmacist.

How much to take

The dose varies from person to person. Your doctor will decide the right dose for you.

The usual starting dose for adults is 500 mg one to two times a day. Your doctor may increase or decrease the dose, depending on your blood glucose levels. The maximum recommended dose is 1000 mg three times a day.

The elderly and people with kidney problems may need smaller doses.

Children & Adolescents:

The usual starting dose for children from 10 years of age and adolescents is one tablet of 500 mg or 850 mg once daily. Your doctor may increase or decrease the dose, depending on your blood glucose levels.

The maximum recommended dose is 2 g taken as two or three divided doses.

If your child has diabetes that is resistant to insulin and is being treated in hospital, your child's doctor will decide the dose.

How to take Diabex

Swallow the tablets with a glass of water. The 500 mg and 1000 mg tablets can be divided in half along the breakline, if advised by your doctor or pharmacist.

When to take Diabex

Take Diabex during or immediately after food. This will reduce the chance of a stomach upset.

Take your medicine at about the same time each day. Taking it at the same time each day will have the best effect. It will also help you remember when to take it.

How long to take Diabex for

Keep taking Diabex for as long as your doctor recommends. Diabex will help control diabetes but will not cure it. Most people will need to take Diabex on a long-term basis.

If you forget to take Diabex

If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to.

Otherwise, take the missed dose as soon as you remember (with food), and then go back to taking your tablets as you would normally.

Do not take a double dose to make up for the dose you missed.

If you are not sure what to do, ask your doctor or pharmacist.

If you take too much Diabex (overdose)

Immediately telephone your doctor, or the Poisons Information Centre (telephone 13 11 26), or go to Accident and Emergency at the nearest hospital, if you think you or anyone else may have taken too much Diabex. Do this even if there are no signs of discomfort or poisoning. If you take too much Diabex, you may feel sleepy, very tired, sick, vomit, have trouble breathing and have unusual muscle pain, stomach pain or diarrhoea. These may be early signs of a serious condition called lactic acidosis (build up of lactic acid in the blood).

You may also experience symptoms of hypoglycaemia (low blood glucose). This usually only happens if you take too much Diabex together with other medicines for diabetes or with alcohol.

If you do experience any signs of hypoglycaemia, raise your blood glucose quickly by eating jelly beans, sugar or honey, drinking a non-diet soft drink or taking glucose tablets.

While you are taking Diabex

Things you must do

Make sure that you, your friends, family and work colleagues can recognise the symptoms of hypoglycaemia and hyperglycaemia and know how to treat them.

HYPOGLYCAEMIA

Diabex does not normally cause hypoglycaemia, although you may experience it if you take other medicines for diabetes such as sulfonylureas or repaglinide; or if you also use insulin.

Hypoglycaemia can occur suddenly. Initial signs may include:
weakness, trembling or shaking
sweating
lightheadedness, dizziness, headache or lack of concentration
irritability, tearfulness or crying
hunger
numbness around the lips and tongue.

If not treated promptly, these may progress to:
loss of co-ordination
slurred speech
confusion
fits or loss of consciousness.

If you experience any of the symptoms of hypoglycaemia, you need to raise your blood glucose immediately.

You can do this by doing one of the following:
eating 5 to 7 jelly beans
eating 3 teaspoons of sugar or honey
drinking half a can of non-diet soft drink
taking 2 to 3 concentrated glucose tablets.

Unless you are within 10 to 15 minutes of your next meal or snack, follow up with extra carbohydrates such as plain biscuits, fruit or milk. Taking this extra carbohydrate will prevent a second drop in your blood glucose level.

HYPERGLYCAEMIA

If you notice the return of any of the signs of hyperglycaemia, contact your doctor immediately. Your doctor may need to consider additional or other treatments for your diabetes.

The risk of hyperglycaemia is increased in the following situations:
uncontrolled diabetes
illness, infection or stress
taking less Diabex than prescribed
taking certain other medicines
too little exercise
eating more carbohydrates than normal.

Tell your doctor if you:
become ill
become dehydrated
are injured
have a fever
have a serious infection
are having surgery (including dental surgery).

Your blood glucose may become difficult to control at these times. You may also be more at risk of developing a serious condition called lactic acidosis. At these times, your doctor may replace Diabex with insulin.

Before starting any new medicine, tell your doctor or pharmacist that you are taking Diabex.

Tell all the doctors, dentists and pharmacists who are treating you that you are taking Diabex.

If you become pregnant while taking Diabex, tell your doctor immediately.

Visit your doctor regularly for check ups. Your doctor may want to perform blood tests to check your kidneys, liver, heart and vitamin B12 level while you are taking Diabex.

Check your blood glucose levels regularly. This is the best way to tell if your diabetes is being controlled properly. Your doctor or diabetes educator will show you how and when to do this.

When you start treatment with Diabex, it can take up to two weeks for your blood glucose levels to be properly controlled.

Carefully follow the advice of your doctor and dietician on diet, drinking alcohol and exercise.

Things you must not do

Do not skip meals while taking Diabex.

Do not stop taking Diabex or change the dose without checking with your doctor.

Do not give Diabex to anyone else, even if they have the same condition as you.

Do not use Diabex to treat any other conditions unless your doctor tells you to.

Things to be careful of

If you have to be alert, for example when driving, be especially careful not to let your blood glucose levels fall too low. Low blood glucose levels may slow your reaction time and affect your ability to drive or operate machinery. Drinking alcohol can make this worse. However, Diabex by itself is unlikely to affect how you drive or operate machinery.

If you become sick with a cold, fever or flu, it is very important to continue eating your normal meals. Your diabetes educator or dietician can give you a list of foods to eat on sick days.

When you are travelling, it is a good idea to:
wear some form of identification (e.g. bracelet) showing you have diabetes
carry some form of sugar to treat hypoglycaemia if it occurs, for example, sugar sachets or jelly beans
carry emergency food rations in case of a delay, for example, dried fruit, biscuits or muesli bars
bring enough Diabex with you, so you don't miss any doses.

Side effects

Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Diabex. Diabex helps most people with diabetes but it may have unwanted side effects in some people.

All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.

If you are an elderly person over 65 years of age, report any side effects to your doctor immediately. People over this age may have an increased chance of getting side effects.

Ask your doctor or pharmacist to answer any questions you may have.

Do not be alarmed by this list of possible side effects. You may not experience any of them.

Tell your doctor if you notice any of the following and they worry you:
stomach upset such as feeling sick (nausea), vomiting
taste disturbance, loss of appetite
diarrhoea
red skin rash.

The side effects listed above are generally mild. Stomach upset and diarrhoea are common but usually short-lived. Taking Diabex with meals can help reduce nausea and diarrhoea. Skin rash has been reported rarely.

TELL YOUR DOCTOR IMMEDIATELY OR GO TO ACCIDENT AND EMERGENCY AT THE NEAREST HOSPITAL IF YOU NOTICE ANY OF THE FOLLOWING SYMPTOMS OF LACTIC ACIDOSIS (BUILD UP OF LACTIC ACID IN THE BLOOD):
nausea, vomiting, stomach pain
trouble breathing
feeling weak, tired or generally unwell
unusual muscle pain
sleepiness
dizziness or lightheadedness
shivering, feeling extremely cold
slow heart beat.

LACTIC ACIDOSIS IS A VERY RARE BUT SERIOUS SIDE EFFECT REQUIRING URGENT MEDICAL ATTENTION OR HOSPITALISATION. ALTHOUGH RARE, IF LACTIC ACIDOSIS DOES OCCUR, IT CAN BE FATAL. THE RISK OF LACTIC ACIDOSIS IS HIGHER IN THE ELDERLY, THOSE WHOSE DIABETES IS POORLY CONTROLLED, THOSE WITH PROLONGED FASTING, THOSE WITH CERTAIN HEART CONDITIONS, THOSE WHO DRINK ALCOHOL AND THOSE WITH KIDNEY OR LIVER PROBLEMS.

Tell your doctor if you notice anything that is making you feel unwell. Other side effects not listed above may also occur in some people.

After taking Diabex

Storage

Keep Diabex where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

Keep your tablets in the pack until it is time to take them. If you take the tablets out of the pack they may not keep well.

Keep your Diabex tablets in a cool dry place where the temperature stays below 25°C.

Do not store Diabex or any other medicine in the bathroom or near a sink.

Do not leave Diabex in the car or on window sills. Heat and dampness can destroy some medicines.

Disposal

If your doctor tells you to stop taking Diabex, or your tablets have passed their expiry date, ask your pharmacist what to do with any that are left over.

Product description

What it looks like

Diabex tablets come in 3 strengths:
Diabex 500 mg - white, oblong tablet, scored on one side and marked "DIABEX" on the other. Each pack contains 100 tablets.
Diabex 850 mg - white, round tablet. Each pack contains 60 tablets.
Diabex 1000 mg - white, oval tablet, scored on both sides, with "1000" marked on one side. Each pack contains 90 tablets.

Ingredients

The active ingredient in Diabex is metformin hydrochloride:
each Diabex tablet contains 500 mg of metformin hydrochloride
each Diabex 850 tablet contains 850 mg of metformin hydrochloride
each Diabex 1000 tablet contains 1000 mg of metformin hydrochloride.

The tablets also contain the following inactive ingredients:
povidone
magnesium stearate
hypromellose
macrogol 400 (1000 mg tablets only)
macrogol 8000 (1000 mg tablets only).

The tablets are gluten free.

Supplier

Diabex is supplied in Australia by:

Alphapharm Pty Limited
(ABN 93 002 359 739)
Chase Building 2
Wentworth Park Road
Glebe NSW 2037

Phone: (02) 9298 3999

Medical Information

Phone: 1800 028 365
www.alphapharm.com.au
Australian registration numbers:
Diabex 500 mg- AUST R 40806
Diabex 850 mg - AUST R 57645
Diabex 1000 mg - AUST R 81602

This leaflet was prepared on 6 September 2006.

Registered trade mark of Merck Sante s.a.s.

Preferred Generic
Our preferred generic for this medication is listed below. A generic prescription medicine works in the same way as the existing medicine. What matters is the active ingredient, which is the same in the generic brands and the existing brand. Please click on it below to view the product(s).
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