Consumer Medicine Information
What is in this leaflet?
This leaflet answers some common questions about DIFFERIN. Please read this leaflet carefully before you start using the gel. It does not contain all the information available on this medicine. It does not take the place of talking to your doctor or pharmacist.
All medicines have risks and benefits. Your doctor has weighed the risks of your using DIFFERIN topical gel 0.1% against the benefits expected it will have for you.
If you have concerns about using this medicine ask your doctor or pharmacist.
Keep this leaflet with your tube. You may wish to read it again later.
Before you use DIFFERIN topical gel
Before you use DIFFERIN tell your doctor if you have an allergy to any of the ingredients listed in the section labelled Ingredients.
DIFFERIN topical gel should not be used by women who are pregnant or who plan to become pregnant during treatment because of the risk of adverse effects on fetal development. There have been isolated reports of birth defects in babies born to women using adapalene and other topical drugs with a similar mechanism of action during their pregnancy.
The safety and efficacy of DIFFERIN gel has not been studied in relation to children under the age of 12 years.
What DIFFERIN topical gel is used for and how it works
DIFFERIN topical gel is used for the treatment of acne (blackheads, whiteheads and pimples) of the face, chest or back. The product acts against the abnormal skin processes associated with acne.
How to use DIFFERIN topical gel properly
DIFFERIN gel is for external use only.
DIFFERIN topical gel should not come into contact with the eyes, lips, angles of the nose, mucous membrane and open wounds. If accidental contact occurs rinse thoroughly with water.
Apply DIFFERIN at night. Wash the affected area with a mild cleanser or a mild soap. Rinse thoroughly and pat dry. Apply a thin film of the gel to the areas of acne. Do not simply treat the pimples. Let the DIFFERIN gel dry.
Do not wash your face after applying the gel.
Try not to touch the treated areas overnight.
Be patient, you should notice some clinical improvement after 4-8 weeks and more improvement after further use.
Avoid exposing skin treated with DIFFERIN gel to excessive sunlight. Use a sunscreen cream (SPF 30+) and wear protective clothing if exposure to strong or prolonged sunlight cannot be avoided.
Do not use a sunlamp while treating your skin with DIFFERIN gel. Weather extremes such as wind or cold may also be irritating.
Avoid the use of oil-based makeups and creams. Cosmetic products with an abrasive, drying or peeling action may cause an extra irritant effect.
DIFFERIN topical gel should be used with caution by nursing mothers and only in areas away from the chest.
Do not be discouraged if DIFFERIN causes redness, burning or peeling at the beginning of the treatment. These effects most commonly occur during the first month of treatment and should decrease with continued use.
If a serious reaction occurs, discontinue use of DIFFERIN gel and consult your doctor. If the reaction is less severe use the gel less often or stop for a while until the irritation dies down.
DIFFERIN topical gel 0.1% is a smooth, white gel containing 1mg/g adapalene (0.1% w/w).
Each gram of DIFFERIN topical gel contains:
Active : 1mg/g adapalene.
Inactives : carbomer 980, propylene glycol, poloxamer, disodium edetate, methyl hydroxybenzoate, sodium hydroxide and purified water.
Australian Registration Number Aust R 53918.
In case of overdose
DIFFERIN topical gel is intended for external use only. Applying too much gel will not give you any better results and may cause marked redness, peeling or discomfort.
If swallowed, contact your doctor or poisons centre.
Store below 25 degrees and out of reach of children. Avoid exposure to heat.
Replace the cap tightly after use. Do not use DIFFERIN gel after the 'use by' date on the tube.
Do not use the product if the tube or its seal has been damaged.
Where to go for further information
Should you have any questions regarding this product, please contact your doctor or pharmacist.
Who supplies this medicine
Galderma Australia Pty Ltd
Distributed in New Zealand by
9 Rodborough Road
Frenchs Forest NSW 2086
Pacific Pharmaceuticals Pty Ltd
76 Leonard Road
Date of information
Date of issue of patient information September 1998.
This leaflet provides a summary of some of the important things you need to know about DIFFERIN topical gel 0.1%.
Only your doctor and pharmacist are able to weigh up all the relevant facts and you should consult them about all aspects of this medicine as it relates to you.